Human fusariosis: An emerging infection that is difficult to treat

BG Batista, MA Chaves, P Reginatto… - Revista da Sociedade …, 2020 - SciELO Brasil
Fusarium spp. has been associated with a broad spectrum of emerging infections
collectively termed fusariosis. This review includes articles published between 2005 and …

The Impact of Climate Change on Human Fungal Pathogen Distribution and Disease Incidence

P Salazar-Hamm, TJ Torres-Cruz - Current Clinical Microbiology Reports, 2024 - Springer
Abstract Purpose of Review This review aims to compile the current knowledge on the
impact of climate change on human pathogenic fungi. Ongoing surveillance of the fungal …

Synthesis of novel selenocyanates and evaluation of their effect in cultured mouse neurons submitted to oxidative stress

TEA Frizon, JH Cararo, S Saba… - Oxidative Medicine …, 2020 - Wiley Online Library
Herein, we report the synthesis of novel selenocyanates and assessment of their effect on
the oxidative challenge elicited by hydrogen peroxide (H2O2) in cultured mouse neurons …

Seleno-indoles trigger reactive oxygen species and mitochondrial dysfunction in Leishmania amazonensis

PC Santana Filho, MB da Silva, BNM da Silva, T Fazolo… - Tetrahedron, 2023 - Elsevier
Leishmaniasis is an endemic disease caused by obligate intracellular protozoa of the genus
Leishmania prevalent in the Americas, Africa, and Asia. Therapeutic options are limited for …

Specific Antidermatophytic Activity of Trifluoromethylthiolated Cinnamate Derivatives: A New Approach to the Therapy of Superficial Fungal Infections of the Skin

LCG Bazana, DF Dalla Lana, RF da Silva… - …, 2024 - Wiley Online Library
Dermatomycoses are the most widespread fungal skin infections worldwide and directly
affect patients' quality of life. They are challenging to manage because of the need for …

A chloroacetamide derivative as a potent candidate for fusariosis treatment

G da Rosa Monte Machado, S Neiva Lavorato… - Brazilian Journal of …, 2022 - Springer
Fusariosis has presented a significant increase in their incidence in the last years. This
epidemiological panorama probably is due to the increasing profile of refractory …

Structure-based design of δ-lactones for new antifungal drug development: susceptibility, mechanism of action, and toxicity

DF Dalla Lana, ÂR Carvalho, W Lopes… - Folia microbiologica, 2019 - Springer
Dermatophytes are the etiological agents of cutaneous mycoses, including the prevalent nail
infections and athlete's foot. Candida spp. are opportunistic and emerging pathogens …

Synthesis of isothiosemicarbazones of potential antitumoral activity through a multicomponent reaction involving allylic bromides, carbonyl compounds and …

LS Munaretto, M Ferreira, DP Gouvêa, AJ Bortoluzzi… - Tetrahedron, 2020 - Elsevier
A convenient route for the synthesis of isothiosemicarbazones and 2-hydrazono-1, 3-thiazin-
4-ones through a multicomponent reaction featuring allylic bromides, carbonyl compounds …

[HTML][HTML] Design, synthesis, and evaluation of novel 2-substituted 1, 4-benzenediol library as antimicrobial agents against clinically relevant pathogens

DF Dalla Lana, BG Batista, G da Rosa Machado… - Saudi Pharmaceutical …, 2019 - Elsevier
Abstract Development of new antimicrobial agents, capable of combating resistant and
multidrug-resistant fungal and bacterial clinical strains, is necessary. This study presents the …

Anti-Staphylococcus aureus Methicillin-Resistant (MRSA) Activity of a Novel 3-Chalcogenyl Indole

LB Ferreira, EE da Silva, SAM Lentz… - Scientia …, 2021 - dialnet.unirioja.es
Objetivo: o desenvolvimento de novos antimicrobianos contra Staphylococcus aureus
resistentes à meticilina (MRSA) é uma prioridade para a Organização Mundial da Saúde …