Cytokines and microRNAs in SARS-CoV-2: What do we know?

FZ Rarani, B Rashidi, MHJN Abadi, MR Hamblin… - … Therapy-Nucleic Acids, 2022 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic constitutes a global health
emergency. Currently, there are no completely effective therapeutic medications for the …

[HTML][HTML] A timely systematic review on pangolin research, commercialization, and popularization to identify knowledge gaps and produce conservation guidelines

SP Heighton, P Gaubert - Biological Conservation, 2021 - Elsevier
Conservationists can benefit from encompassing research, social, and economic aspects of
conservation issues to produce holistic conservation guidelines. Pangolins have become a …

Genomic analysis reveals a cryptic pangolin species

TT Gu, H Wu, F Yang, P Gaubert… - Proceedings of the …, 2023 - National Acad Sciences
Eight extant species of pangolins are currently recognized. Recent studies found that two
mitochondrial haplotypes identified in confiscations in Hong Kong could not be assigned to …

Trafficked Malayan pangolins contain viral pathogens of humans

W Shi, M Shi, TC Que, XM Cui, RZ Ye, LY Xia… - Nature …, 2022 - nature.com
Pangolins are the most trafficked wild animal in the world according to the World Wildlife
Fund. The discovery of SARS-CoV-2-related coronaviruses in Malayan pangolins has …

Gene expression variability across cells and species shapes innate immunity

T Hagai, X Chen, RJ Miragaia, R Rostom, T Gomes… - Nature, 2018 - nature.com
As the first line of defence against pathogens, cells mount an innate immune response,
which varies widely from cell to cell. The response must be potent but carefully controlled to …

Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database

A Bissett, A Fitzgerald, T Meintjes, PM Mele, F Reith… - GigaScience, 2016 - Springer
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

[HTML][HTML] Should we discount the laboratory origin of COVID-19?

R Segreto, Y Deigin, K McCairn, A Sousa… - Environmental chemistry …, 2021 - Springer
There is a near-consensus view that severe acute respiratory syndrome coronavirus (SARS-
CoV-2), the causative agent of COVID-19, has a natural zoonotic origin; however, several …

Pangolins lack IFIH1/MDA5, a cytoplasmic RNA sensor that initiates innate immune defense upon coronavirus infection

H Fischer, E Tschachler, L Eckhart - Frontiers in immunology, 2020 - frontiersin.org
Zoonotic infections are an imminent threat to human health. Pangolins were recently
identified as carriers and intermediate hosts of coronaviruses. Previous research has shown …

SARS-CoV-2/COVID-19: evolving reality, global response, knowledge gaps, and opportunities

MF Osuchowski, F Aletti, JM Cavaillon, SB Flohe… - Shock, 2020 - journals.lww.com
Approximately 3 billion people around the world have gone into some form of social
separation to mitigate the current severe acute respiratory syndrome coronavirus 2 (SARS …

[PDF][PDF] Genomic consequences of population decline in critically endangered pangolins and their demographic histories

JY Hu, ZQ Hao, L Frantz, SF Wu, W Chen… - National Science …, 2020 - academic.oup.com
Pangolins are among the most critically endangered animals due to heavy poaching and
worldwide trafficking. However, their demographic histories and the genomic consequences …