Alginate microparticles as oral colon drug delivery device: A review

L Agüero, D Zaldivar-Silva, L Peña, ML Dias - Carbohydrate polymers, 2017 - Elsevier
The increase in the research interest on alginate microparticles in pharmaceutical and
biomedical areas confirms its potential use as an effective matrix for drug and cell delivery …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Polysaccharide-based micro/nanocarriers for oral colon-targeted drug delivery

L Zhang, Y Sang, J Feng, Z Li, A Zhao - Journal of drug targeting, 2016 - Taylor & Francis
Oral colon-targeted drug delivery has attracted many researchers because of its distinct
advantages of increasing the bioavailability of the drug at the target site and reducing the …

Engineering thermo/pH-responsive lactoferrin nanostructured microbeads for oral targeting of colorectal cancer

AS Abd Elhamid, L Heikal, DA Ghareeb… - ACS Biomaterials …, 2024 - ACS Publications
Aim: Colorectal cancer is an extremely aggressive form of cancer that often leads to death.
Lactoferrin shows potential for targeting and treating colorectal cancer; however, oral …

Guar gum micro-particles for targeted co-delivery of doxorubicin and metformin HCL for improved specificity and efficacy against colon cancer: in vitro and in vivo …

RK Kang, N Mishr, VK Rai - Aaps Pharmscitech, 2020 - Springer
Doxorubicin and Metformin HCL is a known chemotherapeutic combination that wipes out
tumors and prevents their recurrence. However, limited site specificity confines its …

Development of nitazoxanide-loaded colon-targeted formulation for intestinal parasitic infections: centre composite design-based optimization and characterization

C Bharti, U Nagaich, J Pandey, S Jain… - Future Journal of …, 2020 - Springer
Background The current investigation is focused on the development and characterization of
Eudragit S100 coated nitazoxanide-loaded microbeads as colon-targeted system utilizing …

Quality by Design Approach for Optimization of 5-Fluorouracil Microbeads Using Box–Behnken Design and Desirability Function for Colon Targeting

AK Pandey, US Sara - Journal of Pharmaceutical Innovation, 2023 - Springer
Purpose The main objective was to develop and optimize a multiparticulate system of 5-
fluorouracil through the Box–Behnken design (BBD) and desirability function and coating of …

[HTML][HTML] Preparation, evaluation and optimization of multiparticulate system of mebendazole for colon targeted drug delivery by using natural polysaccharides

KH Ramteke, VB Jadhav, NS Kulkarni… - Advanced …, 2015 - ncbi.nlm.nih.gov
Purpose: A Multiparticulate system of Mebendazole was developed for colon targeted drug
delivery by using natural polysaccharides like Chitosan and Sodium-alginate beads …

Surface engineering of resveratrol to improve neuro-protection and functional recovery after spinal cord injury in rat

X Wang, G Li, P Zhang, W Li, X He - Journal of Drug Delivery Science and …, 2019 - Elsevier
To modify surface of resveratrol using nanotechnology that may ensure optimum drug
availability at the spinal cord injury site and reduce its dosing frequency. Chitosan coated …

Exploiting microspheres as a therapeutic proficient doer for colon delivery: A review

A Vats, K Pathak - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Colon-specific drug delivery systems have recently gained importance for
delivering a variety of therapeutic agents via oral route. This mode offers the feasibility of …