Synthesis and functionalization of hyperbranched polymers for targeted drug delivery

A Kavand, N Anton, T Vandamme, CA Serra… - Journal of Controlled …, 2020 - Elsevier
Hyperbranched polymers (HBPs) have found use in a wide range of applications, such as
optical, electronic and magnetic materials, coatings, additives, supramolecular chemistry …

Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery

A Than, C Liu, H Chang, PK Duong… - Nature …, 2018 - nature.com
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …

A review on engineered magnetic nanoparticles in Non-Small-Cell lung carcinoma targeted therapy

LM Ngema, SA Adeyemi, T Marimuthu… - International Journal of …, 2021 - Elsevier
There are growing appeals for the design of efficacious treatment options for non-small-cell
lung carcinoma (NSCLC) as it accrues to~ 85% cases of lung cancer. Although platinum …

PI3Kgamma Inhibitor Attenuates Immunosuppressive Effect of Poly(l‐Glutamic Acid)‐Combretastatin A4 Conjugate in Metastatic Breast Cancer

H Qin, H Yu, J Sheng, D Zhang, N Shen… - Advanced …, 2019 - Wiley Online Library
Vascular disrupting agents (VDAs) have great potential for cancer treatment. Poly (l‐
glutamic acid)‐combretastatin A4 conjugate (PLG‐CA4) is a novel class of VDAs. Though it …

PSBinder: A web service for predicting polystyrene surface‐binding peptides

N Li, J Kang, L Jiang, B He, H Lin… - BioMed research …, 2017 - Wiley Online Library
Polystyrene surface‐binding peptides (PSBPs) are useful as affinity tags to build a highly
effective ELISA system. However, they are also a quite common type of target‐unrelated …

[HTML][HTML] Carbon nanotubes targeted to the tumor microenvironment inhibit metastasis in a preclinical model of melanoma

L García-Hevia, R Soltani, J González, O Chaloin… - Bioactive Materials, 2024 - Elsevier
Despite notable progress in cancer therapy, metastatic diseases continue to be the primary
cause of cancer-related mortality. Multi-walled carbon nanotubes (MWCNTs) can enter …

Surface immobilization of anti-VEGF peptide on SPIONs for antiangiogenic and targeted delivery of paclitaxel in non-small-cell lung carcinoma

LM Ngema, SA Adeyemi, T Marimuthu… - ACS Applied Bio …, 2023 - ACS Publications
A design has been established for the surface decoration of superparamagnetic iron oxide
nanoparticles (SPIONs) with anti-vascular endothelial growth factor peptide, HRH, to …

Analysis of compositional bias in a commercial phage display peptide library by next-generation sequencing

AB Sloth, B Bakhshinejad, M Jensen, C Stavnsbjerg… - Viruses, 2022 - mdpi.com
The principal presumption of phage display biopanning is that the naïve library contains an
unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity …

Peptides as diagnostic, therapeutic, and theranostic tools: Progress and future challenges

R Thakur, CR Suri, IP Kaur… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Peptides are emerging as a promising candidate for therapeutic as well as diagnostic
applications within the domain of clinical and scientific research. They are recognized for …

Design and in silico evaluation of a novel cyclic disulfide-rich anti-VEGF peptide as a potential antiangiogenic drug

R Baghban, S Ghasemali, S Farajnia… - International Journal of …, 2021 - Springer
The vascular endothelial growth factor (VEGF) signaling pathway has a crucial role in
regulating tumor angiogenesis. VEGF-A shows prominent interaction with the VEGF receptor …