Characterizing Multidevice Capillary Vibrating Sharp-Edge Spray Ionization for In-Droplet Hydrogen/Deuterium Exchange to Enhance Compound Identification

A DeBastiani, SN Majuta, D Sharif, K Attanayake… - ACS …, 2021 - ACS Publications
Multidevice capillary vibrating sharp-edge spray ionization (cVSSI) source parameters have
been examined to determine their effects on conducting in-droplet hydrogen/deuterium …

Capillary vibrating sharp-edge spray ionization augments field-free ionization techniques to promote conformer preservation in the gas-phase for intractable …

D Sharif, SH Foroushani, K Attanayake… - The Journal of …, 2022 - ACS Publications
Field-free capillary vibrating sharp-edge spray ionization (cVSSI) is evaluated for its ability to
conduct native mass spectrometry (MS) experiments. The charge state distributions for nine …

Combining Field-Enabled Capillary Vibrating Sharp-Edge Spray Ionization with Microflow Liquid Chromatography and Mass Spectrometry to Enhance 'Omics …

SN Majuta, A DeBastiani, P Li… - Journal of the American …, 2021 - ACS Publications
Field-enabled capillary vibrating sharp-edge spray ionization (cVSSI) has been combined
with high-flow liquid chromatography (LC) and mass spectrometry (MS) to establish current …

Direct sub‐atmospheric pressure ionization mass spectrometry: Evaporation/sublimation‐driven ionization is amazing, fundamentally, and practically

S Trimpin, ED Inutan, VS Pagnotti… - Journal of Mass …, 2024 - Wiley Online Library
This paper covers direct sub‐atmospheric pressure ionization mass spectrometry (MS). The
discovery, applications, and mechanistic aspects of novel ionization processes for use in MS …

Nanoflow sheath voltage-free interfacing of capillary electrophoresis and mass spectrometry for the detection of small molecules

YS Elshamy, TG Strein, LA Holland, C Li… - Analytical …, 2022 - ACS Publications
Coupling capillary electrophoresis (CE) to mass spectrometry (MS) is a powerful strategy to
leverage a high separation efficiency with structural identification. Traditional CE-MS …

Development of cVSSI-APCI for the improvement of ion suppression and matrix effects in complex mixtures

ME Pursell, D Sharif, A DeBastiani, C Li… - Analytical …, 2022 - ACS Publications
The new ionization technique termed vibrating sharp-edge spray ionization (cVSSI) has
been coupled with corona discharge to investigate atmospheric pressure chemical …

New Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art

S Trimpin, FS Yenchick, C Lee, K Hoang… - Journal of the …, 2024 - ACS Publications
This Perspective covers discovery and mechanistic aspects as well as initial applications of
novel ionization processes for use in mass spectrometry that guided us in a series of …

μPESI-MS/MS System for Screening and Quantitating Drugs in Plasma Samples

S Zhang, Q Liu, X Qu, Q Li, R Wang, J Tian… - Journal of the …, 2023 - ACS Publications
Recently, we developed a novel microprobe electrospray ionization (μPESI) source and its
coupled MS (μPESI-MS/MS) system. Here, we aimed to widely validate the μPESI-MS/MS …

Associating molecular physicochemical properties with ionization efficiency for compounds in aprotic, polar solvent using field-free and field-enabled cVSSI …

K Jayasundara, S Valentine - 2023 - chemrxiv.org
The relationship between separate molecular physicochemical properties and ionization
efficiency has been investigated for the new ionization technique capillary vibrating sharp …

Label free imaging of biological samples using mass spectrometry imaging and Stimulated Raman scattering microscopy

J Majer - 2023 - orca.cardiff.ac.uk
Unlike fluorescence microscopy techniques, label-free imaging techniques avoid
perturbation of the biological environment, which enable the analysis of samples in their …