Ticagrelor

MF Kabil, ASA Dena, IM El-Sherbiny - Profiles of Drug Substances …, 2022 - Elsevier
Ticagrelor is one of the most recent antiplatelet agents used to inhibit platelet aggregation
via blocking the ADP receptors of the subtype P2Y 12. It belongs to the non-thienopyridine …

Four process-related potential new impurities in ticagrelor: Identification, isolation, characterization using HPLC, LC/ESI–MSn, NMR and their synthesis

N Kumar, SR Devineni, PR Gajjala, DK Gupta… - … of pharmaceutical and …, 2016 - Elsevier
Five process-related impurities were detected in the range of 0.08-0.22% in ticagrelor
laboratory batches by HPLC and LC–MS methods. These impurities were named as TIC Imp …

Identification of the major degradation pathways of ticagrelor

HS Yayé, PH Secrétan, T Henriet, M Bernard… - … of Pharmaceutical and …, 2015 - Elsevier
Ticagrelor is a direct-acting and reversible P2Y 12-adenosine diphosphate (ADP) receptor
blocker used as antiplatelet drug. Forced degradation under various stress conditions was …

[PDF][PDF] UV-Vis spectrophotometric assay determination of oral antiplatelet ticagrelor drug in pharmaceutical formulation: Application to content uniformity

D Pandya, M Patel, R Ghediya, A Shah… - Journal of Chemical and …, 2016 - academia.edu
The purpose of this study is to develop and validate a spectroscopic method for the
antiplatelet drug, Ticagrelor. The method was performed on Pharmaco-model of UV …

[PDF][PDF] An improved assay method for the estimation of ticagrelor hydrochloride by reverse phase liquid chromatography

MA Ambasana, NP Kapuriya, KM Mangtani, KD Ladva - 2016 - researchgate.net
The current investigation was carried out to develop and validate a fairly simple, accurate,
precise, reproducible and robust RP-HPLC method for the estimation of Ticagrelor …

Highly sensitive carbon based sensing utilizing titanium dioxide nanoparticles and multiwalled carbon nanotubes for determination of ticagrelor: pharmacokinetics …

M Rizk, MA Sultan, EA Taha, AK Attia… - Journal of The …, 2017 - iopscience.iop.org
Sensitive, accurate and precise square-wave voltammetric method was developed and
validated for determination of a new antiplatelet drug ticagrelor in drug substance using …

[PDF][PDF] Development and validation of a UV spectrophotometric method for the determination of ticagrelor in bulk form

M Ambasana, N Kapuriya, NJ Faldu, K Ladva - Der Pharmacia Lettre, 2014 - academia.edu
The current study was carried out to develop and validate a simple, accurate, precise,
reproducible and cost effective UV-Visible spectrophotometric method for the estimation of …

[PDF][PDF] Analytical method development and validation studies of ticagrelor tablets by RP-HPLC

K Tabassum, R Sarvesh - International Journal of Applied …, 2017 - academia.edu
Objective: The present study was conducted to develop a simple and precise analytical
method for the estimation of ticagrelor in tablet formulation. Methods: Reverse Phase HPLC …

Promoting vascular healing using nanofibrous ticagrelor-eluting stents

CH Lee, MJ Hsieh, KS Liu, CW Cheng… - International Journal …, 2018 - Taylor & Francis
Objective The current treatment of atherosclerotic coronary heart disease with limus-eluting
stents can lead to incomplete endothelialization and substantial impairment of arterial …

Development of feasible and economic electrochemical sensor based on manganese ferrite nanoparticles (Mn0. 2Fe2. 8O4) for determination of a platelet …

H El-Desoky, M Ghoneim, M Gado… - Journal of The …, 2020 - iopscience.iop.org
An exquisite and efficient voltammetric sensor was developed for determination of a new
antiplatelet agent, Ticagrelor hydrochloride (TIC· HCl). Mn x Fe 3-x O 4 nanoparticles (x= 0.0 …