Elevated protein catabolism and protein malnutrition are common in patients with chronic
kidney disease (CKD) and end-stage renal disease (ESRD). The underlying etiology …

Chronic kidney disease (CKD), defined as the presence of irreversible structural or
functional kidney damages, increases the risk of poor outcomes due to its association with …

Chronic kidney disease (CKD) represents a leading cause of death in the United States.
There is no cure for this disease, with current treatment strategies relying on blood pressure …

The kidneys play a pivotal role in the regulation of electrolyte and acid-base balance. With
progressive loss of kidney function, derangements in electrolytes and acid-base inevitably …

The kidney has the principal role in the maintenance of acid-base balance. Therefore, a
decrease in renal ammonium excretion and a positive acid balance often leading to a …

Heart failure (HF) is a leading cause of morbidity and mortality in patients with chronic
kidney disease (CKD), and the population of CKD patients with concurrent HF continues to …

Aims Acetazolamide inhibits proximal tubular sodium and bicarbonate re-absorption and
improved decongestive response in acute heart failure in the ADVOR trial. It is unknown …

It is well established that an elevated potassium level (hyperkalemia) is associated with a
risk of adverse events including morbidity, mortality and healthcare system cost …

The kidney has the principal role in the maintenance of acid-base balance, and therefore, a
fall in renal net acid excretion and positive H+ balance often leading to reduced serum [HCO …

Metabolic acidosis is not uncommon in CKD and is linked with bone demineralization,
muscle catabolism, and higher risks of CKD progression and mortality. Clinical practice …