Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury

Z Álvarez, AN Kolberg-Edelbrock, IR Sasselli… - Science, 2021 - science.org
The signaling of cells by scaffolds of synthetic molecules that mimic proteins is known to be
effective in the regeneration of tissues. Here, we describe peptide amphiphile …

Anesthesia and analgesia for common research models of adult mice

S Ahmadi-Noorbakhsh, M Farajli Abbasi… - Laboratory animal …, 2022 - Springer
Anesthesia and analgesia are major components of many interventional studies on
laboratory animals. However, various studies have shown improper reporting or use of …

Establishing a mouse contusion spinal cord injury model based on a minimally invasive technique

EYY Elzat, X Fan, Z Yang, Z Yuan, Y Pang… - JoVE (Journal of …, 2022 - jove.com
Using minimally invasive methods to model spinal cord injury (SCI) can minimize behavioral
and histological differences between experimental animals, thereby improving the …

A zebrafish drug screening platform boosts the discovery of novel therapeutics for spinal cord injury in mammals

D Chapela, S Sousa, I Martins, AM Cristóvão, P Pinto… - Scientific reports, 2019 - nature.com
Spinal cord injury (SCI) is a complex condition, with limited therapeutic options, that results
in sensory and motor disabilities. To boost discovery of novel therapeutics, we designed a …

Evaluation of the cardiometabolic disorders after spinal cord injury in mice

AB Ghnenis, C Jones, A Sefiani, AJ Douthitt, AJ Reyna… - Biology, 2022 - mdpi.com
Simple Summary The present study demonstrates severity-dependent effects of a thoracic
T8 injury on cardiometabolic dysfunctions in adult mice. While these chronic cardiometabolic …

[HTML][HTML] Spinal cord injury-induced neurogenic bowel: A role for host-microbiome interactions in bowel pain and dysfunction

AB Willits, L Kader, O Eller, E Roberts, B Bye… - Neurobiology of Pain, 2024 - Elsevier
Background and aims Spinal cord injury (SCI) affects roughly 300,000 Americans with
17,000 new cases added annually. In addition to paralysis, 60% of people with SCI develop …

Combined Gene Therapy and Rehabilitative Approaches to Repair the Corticospinal Tract Following Injury

A Kramer - 2021 - search.proquest.com
Spinal cord injury (SCI) is a condition that has plagued humans for centuries, and still there
is no effective treatment to restore neuronal deficits caused by trauma. Unlike the peripheral …

[PDF][PDF] Versatile Scanning Optical Coherence Tomography for Volumetric Multi-Scale Imaging

H Kim - 2018 - core.ac.uk
The optical imaging has a critical role in biomedical research to analyze functional and
morphological variation of an organ, tissue and even a single cell of animal models. Since …