Carbon–Carbon Bond Cleavage for Late-Stage Functionalization

YF Liang, M Bilal, LY Tang, TZ Wang, YQ Guan… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Molecular oxygen-mediated oxygenation reactions involving radicals

C Tang, X Qiu, Z Cheng, N Jiao - Chemical Society Reviews, 2021 - pubs.rsc.org
Molecular oxygen as a green, non-toxic and inexpensive oxidant has displayed lots of
advantages compared with other oxidants towards more selective, sustainable, and …

Recent Advances in Silver‐Catalyzed Transformations of Electronically Unbiased Alkenes and Alkynes

M Li, W Wu, H Jiang - ChemCatChem, 2020 - Wiley Online Library
Silver, as one of the most ancient coinage metals, has attracted a plethora of attention from
chemists in recent years due to the easy availability, high catalytic efficiency and multiple …

[HTML][HTML] Photo-mediated selective deconstructive geminal dihalogenation of trisubstituted alkenes

H Wang, RW Toh, X Shi, T Wang, X Cong… - Nature …, 2020 - nature.com
Selective deconstructive functionalization of alkenes, other than the well-established olefin
metathesis and ozonolysis, to produce densely functionalized molecular scaffolds is highly …

Copper-Catalyzed Aerobic Aminooxygenation of Cinnamyl N-Alkoxycarbamates via Substrate-Promoted Catalyst Activation

CP McNichol, EM DeCicco, AM Canfield… - ACS …, 2023 - ACS Publications
We report a method for a ligand-enabled, copper-catalyzed aerobic aminooxygenation of
internal alkenes. The synergistic combination of a phenanthroline-based ligand and …

Iodine-Mediated C═C Double Bond Cleavage toward Pyrido[2,1-b]quinazolinones

W Hao, K Li, C Ye, W Yu, J Chang - Organic Letters, 2022 - ACS Publications
A transition-metal-free C═ C double bond cleavage reaction employing molecular iodine is
described. In the presence of K2CO3 as the base, I2-mediated C═ C bond cleavage …

Enantioselective, aerobic copper-catalyzed intramolecular carboamination and carboetherification of unactivated alkenes

T Wdowik, SL Galster, RLL Carmo, SR Chemler - ACS catalysis, 2020 - ACS Publications
Reduction of waste is an important goal of modern organic synthesis. We report herein
oxidase reactivity for enantioselective intramolecular copper-catalyzed alkene …

Selective oxidative cleavage of 3-methylindoles with primary amines affording quinazolinones

J He, J Dong, L Su, S Wu, L Liu, SF Yin, Y Zhou - Organic letters, 2020 - ACS Publications
A selective functionalization of C–C═ C bonds toward N–C═ O bonds is realized by an n-
Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique …

Direct electrooxidation of alkynes to benzoin bis-ethers

Z Yang, F Lu, H Li, Y Zhang, W Lin, P Guo… - Organic Chemistry …, 2020 - pubs.rsc.org
A direct electrochemical oxidation of alkynes for the synthesis of benzoin bis-ethers has
been developed. Various alkynes and alcohols are compatible, generating the desired …

Iron-catalyzed intramolecular acyl nitrene/alkyne metalation for the synthesis of pyrrolo [2, 1-a] isoindol-5-ones

X Lai, JB Liu, YC Wang, G Qiu - Chemical Communications, 2021 - pubs.rsc.org
In this work, by using N-methoxybenzamides as efficient acyl nitrene precursors, an iron-
catalyzed acyl nitrene/alkyne metalation is reported for the synthesis of pyrrolo [2, 1-a] …