Oral delivery of pH-responsive alginate microbeads incorporating folic acid-grafted solid lipid nanoparticles exhibits enhanced targeting effect against colorectal …

K Rajpoot, SK Jain - International journal of biological macromolecules, 2020 - Elsevier
To achieve an enhanced anticancer effect of drug to treat colorectal cancer, a dual-targeted
(ie, ligand-tailored and pH-triggered) multiparticulate system has been designed to deliver …

Nanobioconjugates for signal amplification in electrochemical biosensing

S Cajigas, J Orozco - Molecules, 2020 - mdpi.com
Nanobioconjugates are hybrid materials that result from the coalescence of biomolecules
and nanomaterials. They have emerged as a strategy to amplify the signal response in the …

Functionalized magnetic nanoparticles for biomedical applications

D Gudovan, PC Balaure… - Current …, 2015 - benthamdirect.com
Functionalized magnetic nanoparticles followed two main directions in the field of
biomedical applications: one direction is as image enhancing agents for magnetic …

Irinotecan hydrochloride trihydrate loaded folic acid-tailored solid lipid nanoparticles for targeting colorectal cancer: development, characterization, and in vitro …

K Rajpoot, SK Jain - Journal of microencapsulation, 2019 - Taylor & Francis
Aim: The aim of this investigation was to evaluate the potential of folic acid-tailored solid lipid
nanoparticles (SLNs) for encapsulation as well as for in vitro cytotoxicity study of irinotecan …

Rational design of polysorbate 80 stabilized human serum albumin nanoparticles tailored for high drug loading and entrapment of irinotecan

N Taneja, KK Singh - International Journal of Pharmaceutics, 2018 - Elsevier
Human serum albumin (HSA) nanoparticles are considered to be versatile carrier of
anticancer agents in efficiently delivering the drug to the tumor site without causing any …

Self-assembled polypeptide nanoparticles for intracellular irinotecan delivery

NN Zashikhina, MV Volokitina… - European Journal of …, 2017 - Elsevier
In this research poly (l-lysine)-b-poly (l-leucine)(PLys-b-PLeu) polymersomes were
developed. It was shown that the size of nanoparticles depended on pH of self-assembly …

Synthesis, characterization, and application of honey stabilized inulin nanoparticles as colon targeting drug delivery carrier

S Joseph, M Jadav, R Solanki, S Patel, D Pooja… - International Journal of …, 2024 - Elsevier
Inulin (INU) is a versatile natural polysaccharide primarily derived from chicory roots. INU
possesses the unique quality of evading digestion or fermentation in the early stages of the …

Design and characterization of pH stimuli‐responsive nanofiber drug delivery system: the promising targeted carriers for tumor therapy

F Ozcan, EM Cagil - Journal of Applied Polymer Science, 2021 - Wiley Online Library
New carrier platforms have been designed for an electrospun pyridinium calixarene
nanofiber for controlled drug delivery. First, 5, 11, 17, 23‐tetra‐tert‐butyl‐25, 27‐bis (3 …

Immobilization of carborane derivatives on Ni/Fe nanotubes for BNCT

IV Korolkov, AL Kozlovskiy, YG Gorin… - Journal of Nanoparticle …, 2018 - Springer
The most important limitation for boron neutron capture therapy of cancer is the selective
accumulation of boron compounds in tumor tissues in significant quantities. In this paper, we …

Spectrofluorometric and thermal gravimetric study on binding interaction of thiabendazole with hemoglobin on epoxy-functionalized magnetic nanoparticles

E Maltas, M Ozmen - Materials Science and Engineering: C, 2015 - Elsevier
The interaction of thiabendazole (Tbz) with hemoglobin (Hb) on epoxy-functionalized iron
oxide nanoparticles was presented in this study. The binding capacity of Tbz was …