Trends in extracellular matrix biology

K Kyriakopoulou, Z Piperigkou, K Tzaferi… - Molecular Biology …, 2023 - Springer
Extracellular matrixes (ECMs) are intricate 3-dimensional macromolecular networks of
unique architectures with regulatory roles in cell morphology and functionality. As a dynamic …

Estrogen receptors and extracellular matrix: The critical interplay in cancer development and progression

S Mangani, Z Piperigkou, NE Koletsis… - The FEBS …, 2024 - Wiley Online Library
Cancer remains a significant global health concern. Breast cancer is a multifaceted and
prevalent disease influenced by several factors, among which estrogen receptors (ERs) and …

EGFR is a pivotal player of the E2/ERβ–mediated functional properties, aggressiveness, and stemness in triple‐negative breast cancer cells

K Kyriakopoulou, E Kefali, Z Piperigkou… - The FEBS …, 2022 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is defined by aggressive behavior, limited response to
chemotherapy and lower overall survival rates. The increased metastatic potential of TNBC …

Progesterone receptor membrane component 2 is critical for human placental extravillous trophoblast invasion

T Yokouchi-Konishi, Y Liu, L Feng - Biology of Reproduction, 2023 - academic.oup.com
Proper extravillous trophoblast invasion is essential for normal placentation and pregnancy.
However, the molecular mechanisms by which cytotrophoblasts differentiate into extravillous …

Divergent features of ERβ isoforms in triple negative breast cancer: progress and implications for further research

S Yan, J Wang, H Chen, D Zhang… - Frontiers in Cell and …, 2023 - frontiersin.org
Estrogen receptor β (ERβ) was discovered more than 20 years ago. However, the extent and
role of ERβ expression in breast cancer remain controversial, especially in the context of …

Substrate Type and Concentration Differently Affect Colon Cancer Cells Ultrastructural Morphology, EMT Markers, and Matrix Degrading Enzymes

M Franchi, KA Karamanos, C Cappadone, N Calonghi… - Biomolecules, 2022 - mdpi.com
Aim of the study was to understand the behavior of colon cancer LoVo-R cells (doxorubicin-
resistant) vs. LoVo-S (doxorubicin sensitive) in the initial steps of extracellular matrix (ECM) …

Potential therapeutic role for pigment epithelium-derived factor in post-menopausal breast cancer bone metastasis

N Brook, A Dharmarajan, A Chan… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives This review discusses key oestrogens associated with the circulating pre-and
post-menopausal milieu and how they may impact intratumoral oestrogen levels and breast …

[HTML][HTML] Targeting the crosstalk between estrogen receptors and membrane growth factor receptors in breast cancer treatment: Advances and opportunities

S Yan, J Ji, Z Zhang, M Imam, H Chen, D Zhang… - Biomedicine & …, 2024 - Elsevier
Estrogens play a critical role in the initiation and progression of breast cancer. Estrogen
receptor (ER) α, ERβ, and G protein-coupled estrogen receptor are the primary receptors for …

The movement of mitochondria in breast cancer: internal motility and intercellular transfer of mitochondria

S Libring, ED Berestesky, CA Reinhart-King - Clinical & Experimental …, 2024 - Springer
As a major energy source for cells, mitochondria are involved in cell growth and
proliferation, as well as migration, cell fate decisions, and many other aspects of cellular …

Functionalizable poly-terthiophene/Cu 2 O heterojunction constructed in situ for sensitive photoelectrochemical detection of long non-coding RNA markers

X Pang, R Liu, X Lv, W Lu, L Sun, Q Wang, Z Li… - RSC …, 2024 - pubs.rsc.org
A photoelectrochemical (PEC) sensor based on the poly-2, 2, 5, 2-terthiophene
(pTTh)/Cu2O heterojunction was constructed and applied for the detection of long non …