Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). It is characterized by a progressive loss of dopaminergic neurons …

Abnormal α-synuclein aggregation is a key pathological feature of a group of
neurodegenerative diseases known as synucleinopathies, which include Parkinson's …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …

The clinical diagnosis of synucleinopathies, including Parkinson's disease (PD), dementia
with Lewy bodies (DLB), and multiple system atrophy (MSA), is challenging, especially at an …

Background We assessed the clinimetric properties of ataxia rating scales and functional
tests, and made recommendations regarding their use. Methods A systematic literature …

Multiple system atrophy (MSA) is a rare and fatal neurodegenerative disease with limited
symptomatic treatment options. Aggregation of α‐synuclein in oligodendrocytes is believed …

Objective A recessive biallelic repeat expansion,(AAGGG) exp, in the RFC1 gene has been
reported to be a frequent cause of late‐onset ataxia. For cerebellar ataxia, neuropathy, and …

Many neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease,
are characterised by the accumulation of misfolded protein deposits in the brain, leading to a …

Objectives To evaluate the difference of tau burden between patients with progressive
supranuclear palsy (PSP) and healthy controls (HCs) or other neurodegenerative diseases …

Myelin, the membrane surrounding neuronal axons, is critical for central nervous system
(CNS) function. Injury to myelin-forming oligodendrocytes (OL) in chronic neurological …