Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

T Sorsa, UK Gursoy, S Nwhator… - Periodontology …, 2016 - Wiley Online Library
Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

Realizing the clinical utility of saliva for monitoring oral diseases

JL Ebersole, H Hasturk, M Huber… - Periodontology …, 2024 - Wiley Online Library
In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

Salivary biomarkers and their application in the diagnosis and monitoring of the most common oral pathologies

L Melguizo-Rodríguez, VJ Costela-Ruiz… - International journal of …, 2020 - mdpi.com
Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner—
and the results of its analysis complement clinical and histopathological findings in the …

Salivary markers of oxidative stress in oral diseases

L Tóthová, N Kamodyova, T Červenka… - Frontiers in cellular and …, 2015 - frontiersin.org
Saliva is an interesting alternative diagnostic body fluid with several specific advantages
over blood. These include non-invasive and easy collection and related possibility to do …

Salivary cytokines as biomarkers of periodontal diseases

KM Jaedicke, PM Preshaw, JJ Taylor - Periodontology 2000, 2016 - Wiley Online Library
Research into biomarkers of periodontitis is driven by mainly three targets: to identify 'at
risk'patients before periodontal tissue destruction occurs; to determine disease activity and …

Identification of salivary microbiota and its association with host inflammatory mediators in periodontitis

A Lundmark, YOO Hu, M Huss, G Johannsen… - Frontiers in cellular …, 2019 - frontiersin.org
Periodontitis is a microbial-induced chronic inflammatory disease, which may not only result
in tooth loss, but can also contribute to the development of various systemic diseases. The …

Matrix metalloproteinase‐8 as an inflammatory and prevention biomarker in periodontal and peri‐implant diseases

A Al-Majid, S Alassiri, N Rathnayake… - … journal of dentistry, 2018 - Wiley Online Library
Levels of and especially the degree of activation of matrix metalloproteinase (MMP‐8) in oral
fluids (ie, saliva, mouth rinse, gingival crevicular fluid (GCF) and peri‐implantitis sulcular …

Salivary biomarkers for detection of systemic diseases

N Rathnayake, S Åkerman, B Klinge, N Lundegren… - PloS one, 2013 - journals.plos.org
Background and Objective Analysis of inflammatory biomarkers in saliva could offer an
attractive opportunity for the diagnosis of different systemic conditions specifically in …

Diagnostic accuracy of oral fluids biomarker profile to determine the current and future status of periodontal and peri-implant diseases

SS Gul, AA Abdulkareem, AM Sha, A Rawlinson - Diagnostics, 2020 - mdpi.com
Severe periodontitis is ranked as the sixth most prevalent disease affecting humankind, with
an estimated 740 million people affected worldwide. The diagnosis of periodontal diseases …

Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease

VM Barnes, AD Kennedy, F Panagakos, W Devizio… - PloS one, 2014 - journals.plos.org
Recent studies suggest that periodontal disease and type 2 diabetes mellitus are bi-
directionally associated. Identification of a molecular signature for periodontitis using …