[HTML][HTML] A selective review of the excitatory-inhibitory imbalance in schizophrenia: underlying biology, genetics, microcircuits, and symptoms

Y Liu, P Ouyang, Y Zheng, L Mi, J Zhao… - Frontiers in cell and …, 2021 - frontiersin.org
Schizophrenia is a chronic disorder characterized by specific positive and negative primary
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …

Mast cells, brain inflammation and autism

TC Theoharides, JM Stewart, S Panagiotidou… - European journal of …, 2016 - Elsevier
Increasing evidence indicates that brain inflammation is involved in the pathogenesis of
neuropsychiatric diseases. Mast cells (MCs) are located perivascularly close to neurons and …

[HTML][HTML] Focal brain inflammation and autism

TC Theoharides, S Asadi, AB Patel - Journal of neuroinflammation, 2013 - Springer
Increasing evidence indicates that brain inflammation is involved in the pathogenesis of
neuropsychiatric diseases. Autism spectrum disorders (ASD) are characterized by social …

[HTML][HTML] Reelin, an extracellular matrix protein linked to early onset psychiatric diseases, drives postnatal development of the prefrontal cortex via GluN2B-NMDARs …

J Iafrati, MJ Orejarena, O Lassalle, L Bouamrane… - Molecular …, 2014 - nature.com
Defective brain extracellular matrix (ECM) is a factor of vulnerability in various psychiatric
diseases such as schizophrenia, depression and autism. The glycoprotein reelin is an …

ECM receptors in neuronal structure, synaptic plasticity, and behavior

ME Kerrisk, LA Cingolani, AJ Koleske - Progress in brain research, 2014 - Elsevier
During central nervous system development, extracellular matrix (ECM) receptors and their
ligands play key roles as guidance molecules, informing neurons where and when to send …

Is a subtype of autism an allergy of the brain?

TC Theoharides - Clinical therapeutics, 2013 - Elsevier
BACKGROUND: Autism spectrum disorders (ASDs) are characterized by deficits in social
communication and language and the presence of repetitive behaviors that affect as many …

Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio)

DF Frank, GW Miller, DJ Harvey, SM Brander, J Geist… - Aquatic toxicology, 2018 - Elsevier
Over the last few decades, the pyrethroid insecticide bifenthrin has been increasingly
employed for pest control in urban and agricultural areas, putting humans and wildlife at …

[HTML][HTML] Synapse assembly and neurodevelopmental disorders

P Washbourne - Neuropsychopharmacology, 2015 - nature.com
In this review we examine the current understanding of how genetic deficits associated with
neurodevelopmental disorders may impact synapse assembly. We then go on to discuss …

[HTML][HTML] The long and the short of it: gene and environment interactions during early cortical development and consequences for long-term neurological disease

H Stolp, A Neuhaus, R Sundramoorthi… - Frontiers in psychiatry, 2012 - frontiersin.org
Cortical development is a complex amalgamation of proliferation, migration, differentiation,
and circuit formation. These processes follow defined timescales and are controlled by a …

[HTML][HTML] HERVs expression in autism spectrum disorders

E Balestrieri, C Arpino, C Matteucci, R Sorrentino… - PloS one, 2012 - journals.plos.org
Background Autistic Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental
disorder, resulting from complex interactions among genetic, genomic and environmental …