Gene× environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution

MC Keller - Biological psychiatry, 2014 - Elsevier
Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …

D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

EP Noble - American Journal of Medical Genetics Part B …, 2003 - Wiley Online Library
The D2 dopamine receptor (DRD2) has been one of the most extensively investigated gene
in neuropsychiatric disorders. After the first association of the TaqI A DRD2 minor (A1) allele …

Genetics of dopamine receptors and drug addiction: a comprehensive review

B Le Foll, A Gallo, Y Le Strat, L Lu… - Behavioural …, 2009 - journals.lww.com
Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and
drug-taking behaviours persist despite serious negative consequences. Addictive …

Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine

LM Oswald, DF Wong, M McCaul, Y Zhou… - …, 2005 - nature.com
There is evidence that stress and glucocorticoids alter drug self-administration and
mesolimbic dopamine (DA) activity in preclinical models. The primary purpose of this study …

Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case–control studies and evidence of publication bias

MR Munafo, IJ Matheson, J Flint - Molecular psychiatry, 2007 - nature.com
We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism
and alcoholism, using meta-analytic techniques, and specifically undertook an investigation …

Mind the gap: Why many geneticists and psychological scientists have discrepant views about gene–environment interaction (G× E) research.

LE Duncan, AR Pollastri, JW Smoller - American Psychologist, 2014 - psycnet.apa.org
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders,
many traditional psychological and social science researchers have added, or plan to add …

The influence of gene–environment interactions on alcohol consumption and alcohol use disorders: A comprehensive review

KC Young-Wolff, MA Enoch, CA Prescott - Clinical psychology review, 2011 - Elsevier
Since 2005, a rapidly expanding literature has evaluated whether environmental factors
such as socio-cultural context and adversity interact with genetic influences on drinking …

Partisanship, voting, and the dopamine D2 receptor gene

CT Dawes, JH Fowler - The Journal of Politics, 2009 - journals.uchicago.edu
Previous studies have found that both political orientations (Alford, Funk, and Hibbing) and
voting behavior (Fowler, Baker, and Dawes; Fowler and Dawes) are significantly heritable …

[HTML][HTML] The impact of gene–environment interaction on alcohol use disorders

DM Dick, KS Kendler - Alcohol research: current reviews, 2012 - ncbi.nlm.nih.gov
This article describes three types of gene–environment interactions and the challenges
inherent in interpreting these interactions. It also reports on what is known about gene …

Meta-Analysis of the Association of the Taq1A Polymorphism with the Risk of Alcohol Dependency: A HuGE Gene-Disease Association Review

L Smith, M Watson, S Gates, D Ball… - American journal of …, 2008 - academic.oup.com
The human dopamine 2 receptor Taq1A allele has been implicated as a vulnerability factor
for alcohol dependence in a number of studies and reviews. To determine whether this …