Parkinson's disease: Mechanisms, translational models and management strategies

C Raza, R Anjum - Life sciences, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …

An update on the diagnosis and treatment of Parkinson disease

P Rizek, N Kumar, MS Jog - Cmaj, 2016 - Can Med Assoc
Methods We used Canadian and American national guidelines to inform this review, in
addition to published systematic reviews that were known to us. We identified additional …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

The clinical heterogeneity of Parkinson's disease and its therapeutic implications

JC Greenland, CH Williams‐Gray… - European Journal of …, 2019 - Wiley Online Library
Although Parkinson's disease (PD) is primarily a movement disorder, there are a range of
associated nonmotor symptoms, including cognitive impairment, depression and sleep …

Classification of Parkinson's disease gait using spatial-temporal gait features

F Wahid, RK Begg, CJ Hass… - IEEE journal of …, 2015 - ieeexplore.ieee.org
Quantitative gait assessment is important in diagnosis and management of Parkinson's
disease (PD); however, gait characteristics of a cohort are dispersed by patient physical …

The effects of highly challenging balance training in elderly with Parkinson's disease: a randomized controlled trial

D Conradsson, N Löfgren, H Nero… - … and neural repair, 2015 - journals.sagepub.com
Background. Highly challenging exercises have been suggested to induce neuroplasticity in
individuals with Parkinson's disease (PD); however, its effect on clinical outcomes remains …

Diagnosis and management of Parkinson's disease

A Tarakad, J Jankovic - Seminars in neurology, 2017 - thieme-connect.com
Despite numerous efforts to identify specific and sensitive biomarkers, the diagnosis of
Parkinson's disease (PD) is still based on clinical criteria that include the presence of a …

Older adults and individuals with Parkinson's disease control posture along suborthogonal directions that deviate from the traditional anteroposterior and mediolateral …

M Mangalam, DG Kelty-Stephen, I Seleznov… - Scientific Reports, 2024 - nature.com
A rich and complex temporal structure of variability in postural sway characterizes healthy
and adaptable postural control. However, neurodegenerative disorders such as Parkinson's …

Awareness and current knowledge of Parkinson's disease: a neurodegenerative disorder

AU Khan, M Akram, M Daniyal… - International Journal of …, 2019 - Taylor & Francis
Context: Parkinson's disease (PD) is the second common progressive neurodegenerative
disease, distressing older men and is prevalent Worldwide. Objectives: This article is aimed …

Virtual reality balance training to improve balance and mobility in Parkinson's disease: a systematic review and meta-analysis

E Sarasso, A Gardoni, A Tettamanti, F Agosta… - Journal of …, 2022 - Springer
Background In the last few years, virtual reality (VR) has been increasingly used to
strengthen the effect of balance training (BT) in Parkinson's disease (PD). Objective We …