Mechanical oscillations orchestrate axial patterning through Wnt activation in Hydra

J Ferenc, P Papasaikas, J Ferralli, Y Nakamura… - Science …, 2021 - science.org
Mechanical input shapes cell fate decisions during development and regeneration in many
systems, yet the mechanisms of this cross-talk are often unclear. In regenerating Hydra …

Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium

SL Weevers, AD Falconer, M Mercker, H Sadeghi… - bioRxiv, 2024 - biorxiv.org
The spontaneous emergence of tissue patterns is often attributed to biochemical reaction-
diffusion systems. In Hydra tissue regeneration, the formation of a Wnt signaling center …

Wnt3 expression as a readout of tissue stretching during Hydra regeneration

J Ferenc, P Papasaikas, J Ferralli, Y Nakamura… - bioRxiv, 2020 - biorxiv.org
Mechanical forces shape cell fate decisions during development and regeneration in many
systems. Epithelial lumen volume changes, for example, generate mechanical forces that …