[HTML][HTML] Tyrosine Kinase Inhibitors in Osteosarcoma: Adapting Treatment Strategies
A Assi, M Farhat, MCR Hachem, Z Zalaquett… - Journal of Bone …, 2023 - Elsevier
Osteosarcoma (OS) is an aggressive primary bone malignancy that metastasizes rapidly.
The standard of care has changed little over the previous four decades, and survival rates …
The standard of care has changed little over the previous four decades, and survival rates …
Signaling pathways and targeted therapies in Ewing sarcoma
K Jia, L Cao, Y Yu, D Jing, W Wu, BA Van Tine… - Pharmacology & …, 2024 - Elsevier
Ewing sarcoma, the second most prevalent malignant bone tumor with potential occurrence
in soft tissues, exhibits a high level of aggressiveness, primarily afflicting children and …
in soft tissues, exhibits a high level of aggressiveness, primarily afflicting children and …
Carbonic anhydrase inhibitors induce ferroptosis through inhibition of AKT/FTH1 signaling in ewing sarcoma tumor cells
D Fayzullina, S Yakushov, K Kantserova, E Belyaeva… - Cancers, 2023 - mdpi.com
Simple Summary Ewing sarcoma (ES) is one of the most common kinds of cancer in
youngsters, and ES relapse after therapy treatment remains a problem. Carbonic …
youngsters, and ES relapse after therapy treatment remains a problem. Carbonic …
[HTML][HTML] Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway
S Dong, Y Xiao, Z Zhu, X Ma, Z Peng… - European Journal of …, 2023 - ncbi.nlm.nih.gov
Metformin can enhance cancer cell chemosensitivity to anticancer drugs. IGF-1R is involved
in cancer chemoresistance. The current study aimed to elucidate the role of metformin in …
in cancer chemoresistance. The current study aimed to elucidate the role of metformin in …