The Colombian bushmasters Lachesis acrochorda (García, 1896) and Lachesis muta (Linnaeus, 1766): snake species, venoms, envenomation, and its management

CA Cañas, S Castaño-Valencia, F Castro-Herrera - Toxicon, 2023 - Elsevier
In Colombia, there are two species of bushmaster snakes, Lachesis acrochorda, which is
distributed mainly in the west of the country (in the Choco region), and Lachesis muta in the …

Structural and pharmacological features of phospholipases A2 from snake venoms

RC de Paula, HC Castro, CR Rodrigues… - Protein and Peptide …, 2009 - ingentaconnect.com
Phospholipases A2 enzymes are found in many biological sources, including snake
venoms. Here we reviewed aspects of PLA2s including biological and structural features …

Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus …

L Sanz, J Escolano, M Ferretti, MJ Biscoglio… - Journal of …, 2008 - Elsevier
We report the proteomic characterization of the venoms of two closely related pit vipers of
the genus Lachesis, L. muta (South American Bushmaster) and L. stenophrys (Central …

Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: biochemical and toxicological characterization

J Fernández, JM Gutiérrez, Y Angulo, L Sanz, P Juárez… - Biochimie, 2010 - Elsevier
Phospholipases A2 (PLA2) are major components of snake venoms, exerting a variety of
relevant toxic actions such as neurotoxicity and myotoxicity, among others. Since the …

Analysis of the uterine lumen in fertility-classified heifers: I. Glucose, prostaglandins, and lipids

JGN Moraes, SK Behura, TW Geary… - Biology of …, 2020 - academic.oup.com
Survival and growth of the bovine conceptus (embryo and associated extraembryonic
membranes) are dependent on endometrial secretions or histotroph found in the uterine …

A new acidic myotoxic, anti-platelet and prostaglandin I2 inductor phospholipase A2 isolated from Bothrops moojeni snake venom

NA Santos-Filho, LB Silveira, CZ Oliveira… - Toxicon, 2008 - Elsevier
Phospholipase A2 (PLA2, EC 3.1. 1.4), a major component of snake venoms, specifically
catalyzes the hydrolysis of fatty acid ester bonds at position 2 of 1, 2-diacyl-sn-3 …

Effect of Seaweed-Derived Fucoidans from Undaria pinnatifida and Fucus vesiculosus on Coagulant, Proteolytic, and Phospholipase A2 Activities of Snake Bothrops …

C Castro-Pinheiro, LCSP Junior, EF Sanchez… - Toxins, 2024 - mdpi.com
Background: Snakebite envenomation (SBE) causes diverse toxic effects in humans,
including disability and death. Current antivenom therapies effectively prevent death but fail …

Cloning and Identification of a Complete cDNA Coding for a Bactericidal and Antitumoral Acidic Phospholipase A2 from Bothrops jararacussu Venom

PG Roberto, S Kashima, S Marcussi, JO Pereira… - The protein journal, 2004 - Springer
In order to better understand the function of acidic phospholipases A 2 (PLA 2 s) from snake
venoms, expressed sequence tags (ESTs) that code for acidic PLA 2 s were isolated from a …

An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom

LJ Vargas, M Londoño, JC Quintana, C Rua… - … and physiology part B …, 2012 - Elsevier
Snake venoms are complex mixtures of proteins among which both basic and acidic
phospholipases A2 (PLA2s) can be found. Basic PLA2s are usually responsible for major …

Purification and Biochemical Characterization of Three Myotoxins from Bothrops mattogrossensis Snake Venom with Toxicity against Leishmania and Tumor Cells

AA Moura, AM Kayano, GA Oliveira… - BioMed research …, 2014 - Wiley Online Library
Bothrops mattogrossensis snake is widely distributed throughout eastern South America and
is responsible for snakebites in this region. This paper reports the purification and …