EZH2 is a component of the polycomb repressive complex 2 (PRC2), which is a highly
conserved histone methyltransferase that methylates lysine 27 of histone 3. EZH2 mutations …

Background/Aim: Accumulated evidence has supported the hypothesis that the functional
polymorphisms of matrix metalloproteinases (MMP) were associated with the risk of various …

Background/Aim: Metalloproteinases (MMPs) are a family of proteases which have been
shown to be overexpressed in various types of cancers. However, the contribution of MMP1 …

Background/Aim: Accumulated evidence has supported the notion that matrix
metalloproteinase (MMP) genotypes are associated with the susceptibility of many types of …

Background Although the relationship between several single nucleotide polymorphisms
(SNPs) of the oncogene EZH2 and cancer risk has been assessed by some case–control …

Background/Aim: The breakage of matrix metalloproteinases (MMPs) has been reported to
be one of the mechanisms required for tumor invasion, and the expression of MMP-7 in …

Aim: There is very little literature reporting the association of matrix metalloproteinase-1
(MMP1) with personal susceptibility to bladder cancer. In the current study, we carried out …

Aim: To evaluate the contribution of ERCC1 rs11615 and rs3212986 genotypes regarding
the risk of colorectal cancer (CRC) in Taiwan. Materials and Methods: In this case–control …

Background/Aim: Nijmegen breakage syndrome 1 (NBS1) is a component of
MRE11/RAD50/NBS1 complex (MRN) that plays a critical role in the cellular response to …

Background/Aim: Matrix metalloproteinases (MMPs) control the homeostasis of the
extracellular matrix and their genetic polymorphisms may contribute to cancer susceptibility …