Chronic obstructive pulmonary disease (COPD), the frequently fatal pathology of the
respiratory tract, accounts for half a billion cases globally. COPD manifests via chronic …

Cancer treatment generally relies on tumor ablative techniques that can lead to major
functional or disfiguring defects. These post-therapy impairments require the development of …

In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for
refractory inflammatory diseases and engineered MSCs have appeared on the market as …

When mesenchymal stem cells (MSCs) are used for therapy of immunological pathologies,
they get into an inflammatory environment, altering the effectiveness of the treatment. To …

Recently, it has been described that programmed cell death protein 1 (PD-1) overexpressing
melanoma cells are highly aggressive. However, until now it has not been defined which …

The treatment of metastatic breast cancer remained a challenge despite the recent
breakthrough in the immunotherapy regimens. Here, we addressed the multidimensional …

Introduction: One route of translating the information encoded in the glycan chains of cellular
glycoconjugates into physiological effects is via receptor (lectin) binding. A family of …

Mesenchymal stem or stromal cells (MSCs) act on different components of the immune
response including macrophages (MΦs). Therefore this study has been committed to …

Background: Galectin 1 (GAL1), an animal lectin is well characterized in the context of
cancer, tumor environment, but its physiological roles in obesity remain to be demonstrated …

The advent of immunotherapy has revolutionized cancer treatments. However, the
application of immune checkpoint inhibitors may entail severe side effects, with the risk of …