Ensuring adequate anticoagulation for patients requiring cardiac surgery and
cardiopulmonary bypass (CPB) is important due to the adverse consequences of …

During sepsis, an initial prothrombotic shift takes place, in which coagulatory acute-phase
proteins are increased, while anticoagulatory factors and platelet count decrease. Further …

Background: Exposure of blood to polyanionic artificial surfaces, for example, during
cardiopulmonary bypass (CPB), induces a highly procoagulant condition requiring strong …

Clinical practice shows that a critical unmet need in the field of medical device‐associated
thrombosis prevention is the availability of an anticoagulant therapy without hemorrhagic …

The current study aims to evaluate whether prophylactic anticoagulation using argatroban or
an increased dose of unfractionated heparin (UFH) is effective in achieving the targeted …

Extracorporeal circuits including renal replacement therapy, extracorporeal membrane
oxygenation, and ventricular assist devices are increasingly used in critically ill patients. The …

Background. Unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) are
being used for preoperative management of critical coronary artery disease. However …

Introduction Achieving optimal anticoagulation during coronary artery bypass graft (CABG)
surgery remains a challenge, with variations in heparin response attributed to differences in …

Ensuring adequate anticoagulation for patients requiring cardiac surgery and
cardiopulmonary bypass is important due to the adverse consequences of inadequate …

Резюме Существенное место в современной клинической практике занимают прямые
антикоагулянты–гепарины. Их использование позволяет решить целый ряд задач …