Perspective—challenges in biomedical analysis: from classical sensors to stochastic sensors

RI Stefan-van Staden - ECS Sensors Plus, 2022 - iopscience.iop.org
Biomedical analysis needs fast reliable screening methods able to identify and also quantify
substances of clinical interest. Diseases such as, cancer, diabetes, corona, influenza, stroke …

High-Sensitivity Detection of the Lung Cancer Biomarker CYFRA21-1 in Serum Samples Using a Carboxyl-MoS2 Functional Film for SPR-Based Immunosensors

NF Chiu, HT Yang - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
We constructed a novel surface plasmon resonance (SPR) detection assay using carboxyl-
functionalized molybdenum disulfide (carboxyl-MoS2) nanocomposites as a signal …

based point of care diagnostics for cancer biomarkers

P Bhardwaj, B Arora, S Saxena, S Singh… - Sensors & …, 2024 - pubs.rsc.org
Early detection of cancers is key to a better prognosis. Advanced proteomics and genomic
detection techniques offer great specificity and sensitivity, however, delayed symptomatic …

Molecular recognition and quantification of MLH1, MSH2, MSH6, PMS2, and KRAS in biological samples

RI Stefan-van Staden, RM Ilie-Mihai, M Coros… - ECS Sensors …, 2022 - iopscience.iop.org
Two stochastic sensors based on modification of nitrogen and boron dopped exfoliated
graphene with a complex of protoporphyrin and cobalt, were used for molecular recognition …

Clinicopathological Significance and Prognostic Values of Long Noncoding RNA BCYRN1 in Cancer Patients: A Meta‐Analysis and Bioinformatics Analysis

X Han, Y Wang, R Zhao, G Zhang, C Qin… - Journal of …, 2022 - Wiley Online Library
Background. Although combination therapies have substantially improved the clinical
outcomes of cancer patients, the prognosis and early diagnosis remain unsatisfactory. As a …

The influence of Heavy Metals on gastric tumorigenesis

L Wang, C Miao, Y He, H Li, S Zhang, K Li… - Journal of …, 2022 - Wiley Online Library
Objectives. This study aimed to observe the relationship among heavy metals concentration,
microsatellite instability (MSI), and human epidermal growth factor receptor type 2 (HER2) …

Simultaneous analysis of MLH1, MSH2, MSH6, PMS2 and KRAS in patients with gastric and colon cancer using stochastic sensors

DC Gheorghe, RI Stefan-van Staden, F Pogacean… - Chemosensors, 2022 - mdpi.com
Two stochastic sensors were characterized and validated for the molecular identification and
quantification of MLH1, MSH2, MSH6, PMS2 and KRAS in biological samples using two …

2D enantioselective disposable stochastic sensor for fast real-time enantioanalysis of glutamine in biological samples

RI Stefan-van Staden, MI Bogea, RM Ilie-Mihai… - Symmetry, 2023 - mdpi.com
As protein is both a structural component and a metabolic intermediary, amino acids play a
crucial function in the body. When it comes to proteins, only the L-configuration of chiral …

Ultrasensitive assay of 8-hydroxy-2′-deoxyguanosine in whole blood using carbon nanotubes based stochastic microsensors

RI Stefan-van Staden, OR Musat - Microchemical Journal, 2023 - Elsevier
hydroxy-2′-deoxyguanosine assay is having an important role in carcinogenesis, and
accordingly is recognized as a discriminatory biomarker for early detection of breast cancer …

Diagnostic value of imaging combined with tumor markers in early detection of lung cancer

SJ Wei, LP Wang, JY Wang, JX Ma, FB Chuan… - Frontiers in …, 2021 - frontiersin.org
Objective: The objective of this research is to explore the diagnostic value of imaging plus
tumor markers in the early detection of lung cancer. Methods: Sixty patients with lung cancer …