Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

The human gut is a composite anaerobic environment with a large, diverse and dynamic
enteric microbiota, represented by more than 100 trillion microorganisms, including at least …

Variations in N-acylethanolamines (NAE) levels are associated with obesity and metabolic
comorbidities. Their role in the gut remains unclear. Therefore, we generated a mouse …

The endocannabinoidome encompasses several fatty acid (FA)-derived mediators,
including the endocannabinoid anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG) …

Palatable food can be seductive and hedonic eating can become irresistible beyond hunger
and negative consequences. This is witnessed by the subtle equilibrium between eating to …

Abstract Purpose of Review The endocannabinoid (eCB) system, ie the receptors that
respond to the psychoactive component of cannabis, their endogenous ligands and the …

Bariatric surgery remains the single most effective long-term treatment modality for morbid
obesity, achieved mainly by lowering caloric intake through as yet ill-defined mechanisms …

The fatty acid ethanolamide oleoylethanolamide (OEA) is an endogenous lipid mediator
derived from the monounsaturated fatty acid, oleic acid. OEA is synthesized from membrane …