Immune system aging is characterized by the paradox of immunosenescence (insufficiency)
and inflammaging (over-reaction), which incorporate two sides of the same coin, resulting in …

The significantly higher mortality rates seen in the elderly compared with young children
during the coronavirus disease 2019 (Covid‐19) pandemic is likely to be driven in part by an …

BACKGROUND The presence and reactivation of chronic viral infections, such as EBV,
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …

Background. While inflammation predicts mortality in treated human immunodeficiency virus
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …

Aging is a complex phenomenon leading to numerous changes in the physiological systems
of the body. One of the most important changes, called immunosenescence, occurs in the …

Chronic inflammation in older individuals is thought to contribute to inflammatory, age‐
related diseases. Human monocytes are comprised of three subsets (classical, intermediate …

The impact of intrinsic aging upon human peripheral blood T cell subsets remains
incompletely quantified and understood. This impact must be distinguished from the …

We describe a series of Epstein Barr virus (EBV)-positive circumscribed, ulcerative lesions
associated with various types of immunosuppression (IS). The study group (26 patients) …

Diet is the only known intervention which has been conclusively shown to extend life span. It
can be argued the key role diet has to play in the aging process came to prominence as a …

The decline of the immune system appears to be an intractable consequence of aging,
leading to increased susceptibility to infections, reduced effectiveness of vaccination and …