Immunomodulatory activity of tyrosine kinase inhibitors to elicit cytotoxicity against cancer and viral infection

N Climent, M Plana - Frontiers in pharmacology, 2019 - frontiersin.org
Tyrosine kinase inhibitors (TKIs) of aberrant tyrosine kinase (TK) activity have been widely
used to treat chronic myeloid leukemia (CML) for decades in clinic. An area of growing …

Sex chromosome changes in leukemia: cytogenetics and molecular aspects

S Shahrabi, E Khodadi, F Saba, M Shahjahani… - …, 2018 - Taylor & Francis
Background and objective: Sex chromosome loss (SCL) can occur in older men as a
physiological phenomenon or as an acquired abnormality in leukemia. Loss of chromosome …

Sustained antiviral response against in vitro HIV-1 infection in peripheral blood mononuclear cells from people with chronic myeloid leukemia treated with ponatinib

M Manzanares, F Ramos-Martín… - Frontiers in …, 2024 - frontiersin.org
HIV-1 infection cannot be cured due to long-lived viral reservoirs formed by latently infected
CD4+ T cells.“Shock and Kill” strategy has been considered to eliminate the viral reservoir …

Tyrosine kinase inhibitors: potential use and safety considerations in HIV-1 infection

M Coiras, J Ambrosioni, F Cervantes… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Infection caused by HIV-1 is nowadays a chronic disease due to a highly
efficient antiretroviral treatment that is nevertheless, unable to eliminate the virus from the …

Sustained antiviral response against HIV-1 infection in peripheral blood mononuclear cells from people with chronic myeloid leukemia treated with ponatinib

M Manzanares, F Ramos-Martín, S Rodriguez Mora… - 2024 - repisalud.isciii.es
HIV-1 infection cannot be cured due to long-lived viral reservoirs formed by latently infected
CD4 T cells." Shock and Kill" strategy has been considered to eliminate the viral reservoir …

[PDF][PDF] Amedeo De Nicolò, University of Turin, Italy

C Gavegnano, A D'Avolio, S Soloperto, M Coiras… - 2024 - repisalud.isciii.es
The use of antiretroviral therapy (ART) has transformed the infection by the human
immunodeficiency virus type 1 (HIV-1) into a chronic disease. However, ART must be taken …