Osteopontin (OPN) is a bone sialoprotein involved in osteoclast attachment to mineralised
bone matrix, as well as being a bone matrix protein, OPN is also a versatile protein that acts …

Osteopontin (OPN) was first identified in 1986. The prefix osteo‐means bone; however, OPN
is expressed in other tissues, including liver. The suffix‐pontin means bridge and denotes …

Injectable bone biomaterials like bone cement should be designed and fabricated with
certain biological criteria, which include: 1) recruitment and polarization of the macrophages …

AGE/RAGE signaling has been a well‐studied cascade in many different disease states,
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …

A thick dentin layer forms the bulk of dental mineralized dental tissues. Dentin is capped by
a crown made of highly mineralized and protective enamel, and in the root, it is covered by …

Many biological tissues, such as wood and bone, are fiber composites with a hierarchical
structure. Their exceptional mechanical properties are believed to be due to a functional …

In this review, most of the known and postulated mechanisms of osteopontin (OPN) and its
role in bone remodeling and orthodontic tooth movement are discussed based on available …

Although astrogliosis and microglia activation are characteristic features of multiple sclerosis
(MS) and other central nervous system (CNS) lesions the exact functions of these events are …

Although several major progresses have been introduced in the field of bone regenerative
medicine during the years, current therapies, such as bone grafts, still have many limitations …

The study of biomineralization is not only important to gain an understanding of how mineral-
rich tissues are created in vivo but also because it is a great source of inspiration for the …