Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases

K Das, S Paul, T Mukherjee, A Ghosh, A Sharma… - Cells, 2023 - mdpi.com
Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …

The truth is out there: biological features and clinical indications of Extracellular vesicles from human perinatal stem cells

E Russo, G Alberti, S Corrao, CV Borlongan, V Miceli… - Cells, 2023 - mdpi.com
The potential of perinatal tissues to provide cellular populations to be used in different
applications of regenerative medicine is well established. Recently, the efforts of …

Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases

S Tung, E Delavogia, A Fernandez-Gonzalez… - Seminars in …, 2023 - Elsevier
Preterm birth and intrapartum related complications account for a substantial amount of
mortality and morbidity in the neonatal period despite significant advancements in neonatal …

Models of necrotizing enterocolitis

CM Lopez, MES Sampah, JW Duess, A Ishiyama… - Seminars in …, 2023 - Elsevier
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. The mortality of patients with NEC is …

An emerging frontier in intercellular communication: extracellular vesicles in regeneration

PN Avalos, DJ Forsthoefel - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Regeneration requires cellular proliferation, differentiation, and other processes that are
regulated by secreted cues originating from cells in the local environment. Recent studies …

Current therapy option for necrotizing enterocolitis: Practicalities and challenge

H Wu, K Guo, Z Zhuo, R Zeng, Y Luo, Q Yang… - Frontiers in …, 2022 - frontiersin.org
Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal
disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and …

Comparison and investigation of exosomes from human amniotic fluid stem cells and human breast milk in alleviating neonatal necrotizing enterocolitis

X Hu, R Zhang, H Liang, J An, Y Yang, J Huo… - Stem Cell Reviews and …, 2023 - Springer
In view of the devastating impact of neonatal necrotizing enterocolitis (NEC) on newborns,
the research on its intervention is particularly important. Although exosomes from human …

Treatment of necrotizing enterocolitis by conditioned medium derived from human amniotic fluid stem cells

JS O'Connell, B Li, A Zito, A Ahmed, M Cadete… - PLoS …, 2021 - journals.plos.org
Purpose Necrotizing enterocolitis (NEC) is one of the most distressing gastrointestinal
emergencies affecting neonates. Amniotic fluid stem cells (AFSC) improve intestinal injury …

Extracellular vesicles from perinatal cells for anti-inflammatory therapy

A Cargnoni, A Papait, A Masserdotti… - … in Bioengineering and …, 2021 - frontiersin.org
Perinatal cells, including cells from placenta, fetal annexes (amniotic and chorionic
membranes), umbilical cord, and amniotic fluid display intrinsic immunological properties …

Necrotizing enterocolitis: recent advances in treatment with translational potential

N Ganji, B Li, C Lee, A Pierro - Pediatric Surgery International, 2023 - Springer
Necrotizing enterocolitis (NEC) is one of the most prevalent and devastating gastrointestinal
disorders in neonates. Despite advances in neonatal care, the incidence and mortality due …