Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …

ELISA technology has received great attention in in vitro diagnostics (IVD) due to its high
specificity, sensitivity and high throughput. However, the traditional ELISA technology is …

Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for
clinical control and treatment of virus infection. Aptamers are small single-stranded …

SARS-CoV-2, the causative agent of COVID-19, remains among the main causes of global
mortality. Although antigen/antibody-based immunoassays and neutralizing antibodies …

Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Efficient and timely testing has taken center stage in the management, control, and
monitoring of the current COVID-19 pandemic. Simple, rapid, cost-effective diagnostics are …

The molecular biomarkers are molecules that are closely related to specific physiological
states. Numerous molecular biomarkers have been identified as targets for disease …

A dual recognition biosensor was developed via introducing aptamer strings and molecular
imprinting polymer (MIP) for the selective detection of intact SARS-CoV-2 virus based on …

The COVID-19 pandemic is among the greatest health and socioeconomic crises in recent
history. Although COVID-19 vaccines are being distributed, there remains a need for rapid …