Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …

The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to
insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the …

Epigenetics can be defined as 'the structural adaptation of chromosomal regions so as to
register, signal, or perpetuate altered activity states.'Increased transcription of key regulatory …

SIRT6 is a member of the Sir2-like family in mammals. Recent structural and biochemical
studies have characterized SIRT6 as having deacetylation, defatty-acylation, and mono-ADP …

Aging causes degenerative changes such as epigenetic changes and mitochondrial
dysfunction in skeletal muscle. Exercise can upregulate muscle mitochondrial homeostasis …

Abstract A recent International Diabetes Federation report suggests that more than 463
million people between 20 and 79 years have diabetes. Of the 20 million women affected by …

Exercise is an effective strategy in the prevention and treatment of metabolic diseases.
Alterations in the skeletal muscle proteome, including post-translational modifications …

Exercise training causes epigenetic changes in skeletal muscle, although it is unclear how
resistance exercise (RE) affects histone modifications. The present study was carried out to …

Cell regulatory networks are the determinants of cellular homeostasis. Any alteration to
these networks results in the disturbance of cellular homeostasis and induces cells towards …

The increase in blood glucose causes a myriad of pathways and molecular components to
malfunction, leading to diabetes. Diabetes affects each organ differently by activating distinct …