In the past few years, there has been increasing focus on the use of messenger RNA
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …

The field of chimeric antigen receptor (CAR) modified T cell therapy has rapidly expanded in
the past few decades. As of today, there are six CAR T cell products that have been …

Vaccination is a key component of public health policy with demonstrated cost-effective
benefits in protecting both human and animal populations. Vaccines can be manufactured …

Faced with the challenges posed by infectious diseases and cancer, nucleic acid vaccines
present excellent prospects in clinical applications. Compared with traditional vaccines …

Messenger RNA (mRNA) is now in the limelight as a powerful tool for treating various
human diseases, especially malignant tumors, thanks to the remarkable clinical outcomes of …

The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has urged scientists to present some novel vaccine platforms during this pandemic to …

Engineered T cells expressing chimeric antigen receptors (CARs) have been proven as
efficacious therapies against selected hematological malignancies. However, the approved …

Endometriosis is defined as the presence of endometrial-like glands and stroma located
outside the uterine cavity. This common, estrogen dependent, inflammatory condition affects …

Adoptive T cell immunotherapy has received considerable interest in the treatment of
cancer. In recent years, chimeric antigen receptor T cell (CAR T) therapy has emerged as a …

Chimeric antigen receptor T cell (CAR-T) therapy in hematologic malignancies has made
great progress, but there are still some problems. First, T cells from tumor patients show an …