Contribution of the TIM-3/Gal-9 immune checkpoint to tropical parasitic diseases
C Bailly - Acta Tropica, 2023 - Elsevier
Neglected tropical parasitic diseases (NTD) are prevalent in many countries and cost-
effective treatments remain urgently needed. Novel approaches have been proposed to …
effective treatments remain urgently needed. Novel approaches have been proposed to …
Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology, Immunology …
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
The Role of Inflammation in Lymphedema: A Narrative Review of Pathogenesis and Opportunities for Therapeutic Intervention
C Bowman, SG Rockson - International Journal of Molecular Sciences, 2024 - mdpi.com
Lymphedema is a chronic and progressive disease of the lymphatic system characterized by
inflammation, increased adipose deposition, and tissue fibrosis. Despite early hypotheses …
inflammation, increased adipose deposition, and tissue fibrosis. Despite early hypotheses …
Exploring the molecular mechanisms by which secretory phospholipase a2 regulates lymphatic endothelial cell dysfunction by activating macrophages
Z Zhao, P Li, Z Liu, Y Cui, Z Yao, W Chen… - International Journal of …, 2024 - Elsevier
This study offers new insights into the dual role of secretory phospholipase A2 (sPLA2) in
lymphedema, highlighting its impact on lymphatic endothelial cell (LEC) functionality …
lymphedema, highlighting its impact on lymphatic endothelial cell (LEC) functionality …
Profound and selective lymphopaenia in primary lymphatic anomaly patients demonstrates the significance of lymphatic-lymphocyte interactions
J Pearce, L Hadcocks, S Mansour… - Frontiers in …, 2023 - frontiersin.org
Introduction The lymphatic system has a pivotal role in immune homeostasis. To better
understand this, we investigated the impact of Primary Lymphatic Anomalies (PLA) on …
understand this, we investigated the impact of Primary Lymphatic Anomalies (PLA) on …
Reduced Type 2 Innate Lymphocyte Cell Frequencies in Patent Wuchereria bancrofti-Infected Individuals
RSE Tamadaho, J Osei-Mensah, K Arndts, LB Debrah… - Pathogens, 2023 - mdpi.com
Approximately 51 million individuals suffer from lymphatic filariasis (LF) caused mainly by
the filarial worm Wuchereria bancrofti. Mass drug administration (MDA) programs led to a …
the filarial worm Wuchereria bancrofti. Mass drug administration (MDA) programs led to a …
Stage-Dependent Increase of Systemic Immune Activation and CCR5+CD4+ T Cells in Filarial Driven Lymphedema in Ghana and Tanzania
AA Rahamani, S Horn, M Ritter, A Feichtner… - Pathogens, 2023 - mdpi.com
Chronic lymphedema caused by infection of Wuchereria bancrofti is a disfiguring disease
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …
[PDF][PDF] Julian Pearce1, 2, Linda Hadcocks3, Sahar Mansour1, 2, 4, Malou van Zanten1, Steve Jeffery1, Kristiana Gordon2, Pia Ostergaard1, Peter Mortimer1, 2 and …
J Pearce, L Hadcocks, S Mansour, M van Zanten… - 2023 - openaccess.sgul.ac.uk
Methods: The study comprised (i) a retrospective cohort: 177 PLA subjects from the National
Primary Lymphatic Anomaly Register with clinical and laboratory data, and (ii) a prospective …
Primary Lymphatic Anomaly Register with clinical and laboratory data, and (ii) a prospective …
[PDF][PDF] Stage-Dependent Increase of Systemic Immune Activation and CCR5+CD4+ T Cells in Filarial Driven Lymphedema in Ghana and Tanzania. Pathogens 2023 …
AA Rahamani, S Horn, M Ritter, A Feichtner… - 2023 - academia.edu
Chronic lymphedema caused by infection of Wuchereria bancrofti is a disfiguring disease
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …
that leads to physical disability, stigmatization, and reduced quality of life. The edematous …