Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method

VA Duong, TTL Nguyen, HJ Maeng - Molecules, 2020 - mdpi.com
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as
potential drug delivery systems for various applications that are produced from …

Solid lipid nanoparticles: a promising nanomaterial in drug delivery

K Rajpoot - Current pharmaceutical design, 2019 - ingentaconnect.com
The solid lipid nanoparticles (SLNs) usually consists of active drug molecules along with
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …

Gelatin methacrylate hydrogel scaffold carrying resveratrol-loaded solid lipid nanoparticles for enhancement of osteogenic differentiation of BMSCs and effective bone …

B Wei, W Wang, X Liu, C Xu, Y Wang… - Regenerative …, 2021 - academic.oup.com
Critical-sized bone defects caused by traumatic fractures, tumour resection and congenital
malformation are unlikely to heal spontaneously. Bone tissue engineering is a promising …

Buspirone loaded solid lipid nanoparticles for amplification of nose to brain efficacy: Formulation development, optimization by Box-Behnken design, in-vitro …

M Yasir, I Chauhan, A Zafar, M Verma… - Journal of Drug Delivery …, 2021 - Elsevier
The strategies to avoid blood brain barrier are been explored to improve brain targeting
therapeutics in order to ensure potential prospects of nose to brain delivery. In this research …

Solid lipid nanoparticles of curcumin designed for enhanced bioavailability and anticancer efficiency

S Yeo, MJ Kim, YK Shim, I Yoon, WK Lee - ACS omega, 2022 - ACS Publications
Curcumin (Cur) has anticancer properties but exhibits poor aqueous solubility, permeability,
and photostability. In this study, we aimed to develop a solid lipid nanoparticle (SLN) system …

Nose-to-brain delivery of antipsychotics using nanotechnology: A review

MSA Tan, HS Parekh, P Pandey… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Orally-administered antipsychotics are effective in the management of
psychosis-related disorders although generation-specific adverse drug reactions (ADRs) …

Intranasal delivery of chitosan decorated nanostructured lipid carriers of Buspirone for brain targeting: Formulation development, optimization and In-Vivo preclinical …

KM Noorulla, M Yasir, F Muzaffar, S Roshan… - Journal of Drug Delivery …, 2022 - Elsevier
The current research was portrayed to design and optimize the Chitosan (CH) coated
Buspirone-loaded nanostructured lipid carriers (BPE-CH-NLCs) for nose to brain delivery …

Enhanced lymphatic delivery of methotrexate using W/O/W nanoemulsion: in vitro characterization and pharmacokinetic study

JH Jang, SH Jeong, YB Lee - Pharmaceutics, 2020 - mdpi.com
Methotrexate, which is widely used in the treatment of cancer and immune-related diseases,
has limitations in use because of its low bioavailability, short half-life, and tissue toxicity …

Solid lipid nanoparticles

TTL Nguyen, VA Duong - Encyclopedia, 2022 - mdpi.com
Definition Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible
lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce …

Improved anticancer efficacy of methyl pyropheophorbide-a–incorporated solid lipid nanoparticles in photodynamic therapy

S Yeo, TH Lee, MJ Kim, YK Shim, I Yoon, YK Song… - Scientific Reports, 2023 - nature.com
Photodynamic therapy (PDT) is a promising anticancer treatment because it is patient-
friendly and non-invasive. Methyl pyropheophorbide-a (MPPa), one of the chlorin class …