[HTML][HTML] Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

Y Octavia, CG Tocchetti, KL Gabrielson… - Journal of molecular and …, 2012 - Elsevier
The utility of anthracycline antineoplastic agents in the clinic is compromised by the risk of
cardiotoxicity. It has been calculated that approximately 10% of patients treated with …

[HTML][HTML] Doxorubicin induced heart failure: Phenotype and molecular mechanisms

MA Mitry, JG Edwards - IJC heart & vasculature, 2016 - Elsevier
Long term survival of childhood cancers is now more than 70%. Anthracyclines, including
doxorubicin, are some of the most efficacious anticancer drugs available. However, its use …

[HTML][HTML] Согласованное мнение российских экспертов по профилактике, диагностике и лечению сердечно-сосудистой токсичности противоопухолевой …

ЮА Васюк, ГЕ Гендлин, ЕИ Емелина… - Российский …, 2021 - cyberleninka.ru
АВ—атриовентрикулярный (ая) АГ—артериальная гипертензия АД—артериальное
давление АТ—артериальный тромбоз АТО—атеротромботические осложнения АТФ …

Scintigraphic techniques for early detection of cancer treatment–induced cardiotoxicity

LF de Geus-Oei… - Journal of nuclear …, 2013 - Soc Nuclear Med
New antitumor agents have resulted in significant survival benefits for cancer patients.
However, several agents may have serious cardiovascular side effects. Left ventricular …

The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice

A Reis-Mendes, M Ferreira, JA Duarte… - Archives of …, 2023 - Springer
Doxorubicin (DOX) is a potent chemotherapeutic agent used against several cancer types.
However, due to its cardiotoxic adverse effects, the use of this drug may be also life …

Molecular imaging biomarkers in cardiooncology: a view on established technologies and future perspectives

D Kersting, IA Mavroeidi, S Settelmeier… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Novel therapeutic options have significantly improved survival and long-term outcomes in
many cancer entities. Unfortunately, this improvement in outcome is often accompanied by …

Nuclear medicine in the assessment and prevention of cancer therapy-related cardiotoxicity: prospects and proposal of use by the European Association of Nuclear …

M Totzeck, N Aide, J Bauersachs, J Bucerius… - European journal of …, 2023 - Springer
Cardiotoxicity may present as (pulmonary) hypertension, acute and chronic coronary
syndromes, venous thromboembolism, cardiomyopathies/heart failure, arrhythmia, valvular …

Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively

RG Schwartz, D Jain, E Storozynsky - Journal of Nuclear Cardiology, 2013 - Elsevier
The field of cardio-oncology is challenged to address an ever greater spectrum of
cardiotoxicity associated with combination chemotherapy, greater dose intensity, extremes …

Detection of anticancer drug-induced cardiotoxicity using VCAM1-targeted nanoprobes

H Afrin, MN Huda, T Islam, BP Oropeza… - … applied materials & …, 2022 - ACS Publications
Chemotherapy-induced cardiac toxicity is an undesirable yet very common effect that
increases the risk of death and reduce the quality of life of individuals undergoing …

Spatial and temporal heterogeneity of regional myocardial uptake in patients without heart disease under fasting conditions on repeated whole-body 18F-FDG PET/CT

E Inglese, L Leva, R Matheoud… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Imaging of cardiac 18F-FDG uptake is used in the diagnostic evaluation of residual viable
myocardium. Although, originally, hibernating myocardium was identified by a mismatch …