The mechanisms of cardiovascular diseases (CVDs) remain incompletely elucidated. Single-
cell RNA sequencing (scRNA-seq) has enabled the profiling of single-cell transcriptomes at …

Single-cell RNA sequencing (scRNA-seq) is a revolutionary tool for studying the physiology
of normal and pathologically altered tissues. This approach provides information about …

Cardiovascular disease (CVD) is the leading cause of illness and death worldwide.
Numerous studies have been conducted into the underlying mechanisms and molecular …

RNA editing, a common and potentially highly functional form of RNA modification,
encompasses two different RNA modifications, namely adenosine to inosine (A-to-I) and …

The advent of human induced pluripotent stem cells (hiPSCs) and their capacity to be
differentiated into beating human cardiomyocytes (CMs) in vitro has revolutionized human …

In this perspective, we discussed emerging data indicating a role for Notch signalling in
inherited disorders of the heart failure with focus on hypertrophic cardiomyopathy (HCM) …

Nuclear envelope (NE) ruptures are emerging observations in Lamin-related dilated
cardiomyopathy, an adult-onset disease caused by loss-of-function mutations in Lamin A/C …

Determining the pathogenicity of hypertrophic cardiomyopathy–associated mutations in the
β-myosin heavy chain (MYH7) can be challenging due to its variable penetrance and clinical …

Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease, which
can cause heart failure and lead to death. In this study, we performed high‐resolution single …