HIV-1 and human genetic variation

PJ McLaren, J Fellay - Nature Reviews Genetics, 2021 - nature.com
Over the past four decades, research on the natural history of HIV infection has described
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …

Cardiovascular disease and HIV infection

VA Triant - Current HIV/AIDS Reports, 2013 - Springer
The emergence of chronic disease complications in controlled HIV disease has changed the
landscape of HIV clinical care. HIV infection confers an increased cardiovascular disease …

An updated prediction model of the global risk of cardiovascular disease in HIV-positive persons: The Data-collection on Adverse Effects of Anti-HIV Drugs (D: A: D) …

N Friis-Møller, L Ryom, C Smith… - European journal of …, 2016 - journals.sagepub.com
Background With the aging of the population living with HIV, the absolute risk of
cardiovascular disease (CVD) is increasing. There is a need to further facilitate the …

Metabolic disease in HIV infection

JE Lake, JS Currier - The Lancet infectious diseases, 2013 - thelancet.com
The treatment of metabolic disease is becoming an increasingly important component of the
long-term management of patients with well controlled HIV on antiretroviral therapy (ART) …

Protecting and evaluating genomic privacy in medical tests and personalized medicine

E Ayday, JL Raisaro, JP Hubaux… - Proceedings of the 12th …, 2013 - dl.acm.org
In this paper, we propose privacy-enhancing technologies for medical tests and
personalized medicine methods that use patients' genomic data. Focusing on genetic …

Risk of coronary heart disease in patients with HIV infection

MV Zanni, J Schouten, SK Grinspoon… - Nature reviews …, 2014 - nature.com
The lives of individuals infected with HIV who have access to combination antiretroviral
therapy (cART) are substantially prolonged, which increases the risk of developing non …

Management of comorbidities in treated HIV infection: a long way to go: HIV, comorbidities and aging

J Martínez-Sanz, S Serrano-Villar, MJ Vivancos… - International Journal of …, 2022 - Elsevier
Modern ART has now achieved the goal of maintaining HIV RNA suppression with minimum
drug-related toxicities. Indeed, in high-income settings, the main health issues in adult …

British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015

D Churchill, L Waters, N Ahmed, B Angus… - HIV …, 2016 - discovery.ucl.ac.uk
The overall purpose of these guidelines is to provide guidance on best clinical practice in
the treatment and management of adults with HIV infection on antiretroviral therapy (ART) …

Subclinical coronary artery disease in Swiss HIV-positive and HIV-negative persons

PE Tarr, B Ledergerber, A Calmy… - European heart …, 2018 - academic.oup.com
Aims HIV-positive persons have increased cardiovascular event rates but data on the
prevalence of subclinical atherosclerosis compared with HIV-negative persons are not …

Risk of cardiovascular disease associated with exposure to abacavir among individuals with HIV: a systematic review and meta-analyses of results from 17 …

K Dorjee, T Choden, SM Baxi, C Steinmaus… - International journal of …, 2018 - Elsevier
Objectives Abacavir's potential to cause cardiovascular disease (CVD) among people living
with HIV (PLWH) is debated. We conduct a systematic review and meta-analyses to assess …