Chemical and Pharmacological Research of the Plants in Genus Euphorbia

QW Shi, XH Su, H Kiyota - Chemical reviews, 2008 - ACS Publications
The genus Euphorbia is the largest in the spurge family, comprising more than 2000 species
(Figure 1). 1 Some species of the genus Euphorbia have been used as medicinal plants for …

Chemistry and biological activity of secondary metabolites in Euphorbia from Iran

AR Jassbi - Phytochemistry, 2006 - Elsevier
The chemical constituents of some species of Euphorbia, which grow mostly in semi-desert
areas in Iran and on the Alborz Mountains in the north of Tehran, have been found to include …

[HTML][HTML] Antioxidant and cytotoxic activities and phytochemical analysis of Euphorbia wallichii root extract and its fractions

I Ul-Haq, N Ullah, G Bibi, S Kanwal… - Iranian journal of …, 2012 - ncbi.nlm.nih.gov
Euphorbia wallichii a perennial herb growing mainly in Himalayas has been widely used in
folk medicines for its medicinal properties. In the present study, the crude methanolic root …

Jatrophane and rearranged jatrophane-type diterpenes: Biogenesis, structure, isolation, biological activity and SARs (1984–2019)

M Fattahian, M Ghanadian, Z Ali, IA Khan - Phytochemistry reviews, 2020 - Springer
Diterpene compounds specially macrocyclic ones comprising jatrophane, lathyrane,
terracinolide, ingenane, pepluane, paraliane, and segetane skeletons occurring in plants of …

Rearrangement of the Tetra- and Tricyclic Skeletons of Pepluanol B to Access the Core Structures of Tigliane- and Myrsinane-Type Euphorbia Diterpenes

C Wu, J Zhang, M Liu, X Xie, H Li, X She - Organic Letters, 2023 - ACS Publications
Pepluanol B is a new Euphorbia diterpene with an unprecedented tetracyclic backbone.
However, its biogenetic relationship with known Euphorbia diterpenes is unclear. We report …

Antiviral activities of extracts of Euphorbia hirta L. against HIV-1, HIV-2 and SIVmac251

A Gyuris, L Szlavik, J Minarovits, A Vasas, J Molnar… - in vivo, 2009 - iv.iiarjournals.org
The antiretroviral activities of extracts of Euphorbia hirta were investigated in vitro on the
MT4 human T lymphocyte cell line. The cytotoxicities of the extracts were tested by means of …

A flavonoid-rich fraction of Euphorbia peplus attenuates hyperglycemia, insulin resistance, and oxidative stress in a type 2 diabetes rat model

RS Alruhaimi, G Mostafa-Hedeab, MS Abduh… - Frontiers in …, 2023 - frontiersin.org
Background: Type 2 diabetes (T2D) is a metabolic disorder characterized by insulin
resistance (IR) and hyperglycemia. Plants are valuable sources of therapeutic agents for the …

Macrocyclic Diterpenoids from Euphorbia semiperfoliata

G Appendino, S Jakupovic, GC Tron… - Journal of natural …, 1998 - ACS Publications
In addition to known compounds, the aerial parts of E. semiperfoliata afforded an
abietanolide (3), 13 jatrophane polyesters (4− 9, 12, 14− 19), two 4-deoxyphorbol diesters …

In vitro biological propensities and chemical profiling of Euphorbia milii Des Moul (Euphorbiaceae): A novel source for bioactive agents

H Saleem, G Zengin, M Locatelli, A Mollica… - Industrial Crops and …, 2019 - Elsevier
The plants of Euphorbia genus have been extensively studied for their nutritive and
therapeutic purposes. The present research is the foremost effort to investigate and compare …

Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators

MJ Durán-Peña, JMB Ares, IG Collado… - Natural product …, 2014 - pubs.rsc.org
Covering: 1973 to 2013 The biological activities of tigliane, lathyrane, ingenane, casbane,
jatropholane and premyrsinane diterpenoids which contain the gem-dimethylcyclopropyl …