[HTML][HTML] Insights on the CXCL12-CXCR4 axis in hepatocellular carcinoma carcinogenesis

I Ghanem, ME Riveiro, V Paradis, S Faivre… - American journal of …, 2014 - ncbi.nlm.nih.gov
Chemokines, a group of small chemotactic cytokines, and their G-protein-coupled receptors
were originally identified for their ability to mediate various pro-and anti-inflammatory …

The role of chemokines in acute and chronic hepatitis C infection

S Fahey, E Dempsey, A Long - Cellular & Molecular Immunology, 2014 - nature.com
Hepatitis C imposes a significant burden on global healthcare. Chronic infection is
associated with progressive inflammation of the liver which typically manifests in cirrhosis …

LC–MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort

JF Xiao, RS Varghese, B Zhou… - Journal of proteome …, 2012 - ACS Publications
Although hepatocellular carcinoma (HCC) has been subjected to continuous investigation
and its symptoms are well-known, early stage diagnosis of this disease remains difficult and …

CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer

M Benkheil, M Van Haele, T Roskams… - Experimental Cell …, 2018 - Elsevier
Abstract The CCL20/CCR6 chemokine/receptor axis has previously been shown to
contribute to the initiation and progression of hepatocellular carcinoma (HCC) through the …

[HTML][HTML] Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach

F Gao, H Liang, H Lu, J Wang, M Xia, Z Yuan, Y Yao… - Clinical …, 2015 - Springer
Background Epigenetic alterations, such as aberrant DNA methylation of promoter and
enhancer regions, which lead to atypical gene expression, have been associated with …

HCV-induced EGFR-ERK signaling promotes a pro-inflammatory and pro-angiogenic signature contributing to liver cancer pathogenesis

M Benkheil, J Paeshuyse, J Neyts, M Van Haele… - Biochemical …, 2018 - Elsevier
HCV is a major risk factor for hepatocellular carcinoma (HCC). HCC development in
chronically infected HCV patients has until now been attributed to persistent inflammation …

[HTML][HTML] Hepatitis C virus-related hepatocellular carcinoma: An insight into molecular mechanisms and therapeutic strategies

D Selimovic, A El-Khattouti, H Ghozlan… - World journal of …, 2012 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infects more than 170 million people worldwide, and thereby
becomes a series global health challenge. Chronic infection with HCV is considered one of …

Chemokine ligand 20 (CCL20) expression increases with NAFLD stage and hepatic stellate cell activation and is regulated by miR-590-5p

A Hanson, IS Piras, D Wilhelmsen, CD Still, X Chu… - Cytokine, 2019 - Elsevier
Abstract CCL20 (CC chemokine ligand 20) is emerging as an important regulatory molecule
in a pathway common to virus infection, alcoholic hepatitis, and non-alcoholic fatty liver …

Quantitative SERS detection of serum protein biomarkers for assessment of tumor microwave ablation outcomes

Y Ouyang, W Xie, T Tang, X Su, S Xiao, Z Liu… - Chemical Engineering …, 2024 - Elsevier
Microwave ablation (MWA) is widely applied in the treatment of cancer, especially
hepatocellular carcinoma (HCC). However, the lack of indicators for evaluating ablation …

Chemokines in hepatocellular carcinoma: a meta-analysis

X Pan, AC Kaminga, SW Wen, A Liu - Carcinogenesis, 2020 - academic.oup.com
Accumulating evidence suggests that chemokines may play an important role in the
formation and mediating of the immune microenvironment of hepatocellular carcinoma …