The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Global extraintestinal pathogenic Escherichia coli (ExPEC) lineages

AR Manges, HM Geum, A Guo, TJ Edens… - Clinical microbiology …, 2019 - Am Soc Microbiol
SUMMARY Extraintestinal pathogenic Escherichia coli (ExPEC) strains are responsible for a
majority of human extraintestinal infections globally, resulting in enormous direct medical …

Extended-spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options

G Peirano, JDD Pitout - Drugs, 2019 - Springer
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are a major global
public health concern. Presently, Escherichia coli with CTX-Ms are the most common …

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

A Papkou, J Hedge, N Kapel, B Young… - Nature …, 2020 - nature.com
The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread
of a few successful strains, suggesting that some bacteria are genetically pre-disposed to …

Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of …

T Kallonen, HJ Brodrick, SR Harris, J Corander… - Genome …, 2017 - genome.cshlp.org
Escherichia coli associated with urinary tract infections and bacteremia has been intensively
investigated, including recent work focusing on the virulent, globally disseminated, multidrug …

The microbial ecology of Escherichia coli in the vertebrate gut

E Foster-Nyarko, MJ Pallen - FEMS microbiology reviews, 2022 - academic.oup.com
Escherichia coli has a rich history as biology's 'rock star', driving advances across many
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones

L Roer, S Overballe-Petersen, F Hansen, K Schønning… - Msphere, 2018 - Am Soc Microbiol
Escherichia coli sequence type 410 (ST410) has been reported worldwide as an
extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation …

The evolution and transmission of multi-drug resistant Escherichia coli and Klebsiella pneumoniae: the complexity of clones and plasmids

SJ Dunn, C Connor, A McNally - Current opinion in microbiology, 2019 - Elsevier
Highlights•Multi-drug resistance in E. coli and K. pneumoniae is concentrated in a small
number of globally disseminated clones.•Certain plasmids are associated with ESBL and …

Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America

R Zamudio, P Boerlin, R Beyrouthy, JY Madec… - Nature …, 2022 - nature.com
Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for
human and veterinary medicine. ESC resistance (ESC-R) genes have spread worldwide …

[HTML][HTML] Escherichia coli ST131: a multidrug-resistant clone primed for global domination

JDD Pitout, R DeVinney - F1000Research, 2017 - ncbi.nlm.nih.gov
A single extra-intestinal pathogenic Escherichia coli (ExPEC) clone, named sequence type
(ST) 131, is responsible for millions of global antimicrobial-resistant (AMR) infections …