Phyllanthus-derived Naturally-occurring Products: An Overview of their Effects against Viruses in Cell Models

TH Díaz-Herrera, ML Caldas Martínez… - Current Bioactive …, 2024 - benthamdirect.com
Background: Infectious diseases are considered a global public health problem, with viruses
being the predominant infectious agents afflicting the human population. The most used …

Phyllanthus Lignans: A Review of Biological Activity and Elicitation

W Nawfetrias, L Devy, RR Esyanti, A Faizal - Horticulturae, 2024 - mdpi.com
The Phyllanthus genus exhibits a broad distribution spanning across the majority of tropical
and subtropical regions. Due to their ability to synthesize medicinal bioactive compounds …

Discovery and mechanistic study of Imperatorin that inhibits HBsAg expression and cccDNA transcription

F Ren, S Zhao, X He, H Lo, VKW Wong… - Journal of Medical …, 2024 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection remains a significant global health challenge due to
its link to severe conditions like HBV‐related cirrhosis and hepatocellular carcinoma (HCC) …

Glycopentalone, a novel compound from Glycosmis pentaphylla (Retz.) Correa with potent anti-hepatocellular carcinoma activity

PS Sreejith, VV Asha - Journal of ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance Glycosmis pentaphylla (Retz.) Correa is used in
Indian traditional medicine against various liver ailments, including cancer. Aim of the study …

[PDF][PDF] Phyllanthin: a potential lead molecule for the future needs

M Azam, M Ajitha - International Journal of …, 2017 - pdfs.semanticscholar.org
Phyllanthin is an active lignan present in various Phyllanthus species and number of studies
revealed that it exhibits various biological activities that include antioxidant …

Anti-hepatitis B activities of Myanmar medicinal plants: a narrative review of current evidence

YH Linn, WW Ei, LMM Myint, KM Lwin - VirusDisease, 2021 - Springer
Hepatitis B is one of the major burdens for health services and is the leading cause of
morbidity and mortality from cirrhosis of liver and hepatocellular carcinoma. Current …

[PDF][PDF] The long and stumble way to find potential active compounds from plants for defeating hepatitis B and C

AH Saputro, AA Artarini, DH Tjahjono… - Pharmacia, 2022 - pharmacia.pensoft.net
Hepatitis is a liver illness caused by virus such as hepatitis A virus, hepatitis B virus and
hepatitis C virus. Hepatitis B and C are considerably more usual and induce more cirrhosis …

A new fluorescent based screening system for high throughput screening of drugs targeting HBV-core and HBsAg interaction

V Suresh, KA Krishnakumar, VV Asha - Biomedicine & pharmacotherapy, 2015 - Elsevier
The existing screening systems for anti-hepatitis B virus (anti-HBV) drug discovery is time-
consuming mainly due to the laborious detection system it is using. A new fluorescence …

A new LC/MS/MS method for the analysis of phyllanthin in rat plasma and its application on comparative bioavailability of phyllanthin in different formulations after oral …

N Van Long, C Van Men, AV Tuan, N Van Manh… - Pharmacognosy …, 2019 - phcogj.com
Introduction: A simple, short UPLC/MS/MS method for quantitation of phyllanthin in rat
plasma in less than 2 minutes have been developed and fully validated. The validated …

Promising Anticancer Stand-ins of Phyllanthus Species

Simran, Vani, P Kriplani, K Guarve - Current Indian Science, 2023 - benthamdirect.com
Background Phyllanthus species plants along with their active constituent phyllanthin, are
the most widely used plants to cure various diseases. Present studies indicate their …