Cellular communities reveal trajectories of brain ageing and Alzheimer's disease
Alzheimer's disease (AD) has recently been associated with diverse cell states,,,,,,,,,–, yet
when and how these states affect the onset of AD remains unclear. Here we used a data …
when and how these states affect the onset of AD remains unclear. Here we used a data …
RNASE6 is a novel modifier of APOE-ε4 effects on cognition
Abstract Apolipoprotein E4 (APOE-ε4), the strongest common genetic risk factor for
Alzheimer's disease (AD), contributes to worse cognition in older adults. However, many …
Alzheimer's disease (AD), contributes to worse cognition in older adults. However, many …
Effects of copy number variations on longevity in late-onset Alzheimer's disease patients: insights from a causality network analysis
Alzheimer's disease (AD), particularly late-onset Alzheimer's disease (LOAD), is a prevalent
form of dementia that significantly affects patients' cognitive and behavioral capacities and …
form of dementia that significantly affects patients' cognitive and behavioral capacities and …
Elucidating Multimodal Imaging Patterns in Accelerated Brain Aging: Heterogeneity through a Discriminant Analysis Approach Using the UK Biobank Dataset
L Liu, L Lin, S Sun, S Wu - Bioengineering, 2024 - mdpi.com
Accelerated brain aging (ABA) intricately links with age-associated neurodegenerative and
neuropsychiatric diseases, emphasizing the critical need for a nuanced exploration of …
neuropsychiatric diseases, emphasizing the critical need for a nuanced exploration of …
Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse Population
Alzheimer's disease (AD) is a prevalent and costly age-related dementia. Heritable factors
account for 58-79% of variation in late-onset AD, but substantial variation remains in age-of …
account for 58-79% of variation in late-onset AD, but substantial variation remains in age-of …
MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative
Background. Alzheimer's Disease (AD) exhibits a complex molecular and phenotypic profile.
Investigating gene expression plays a crucial role in unraveling the disease's etiology and …
Investigating gene expression plays a crucial role in unraveling the disease's etiology and …
Using multi-omic approaches to identify modulators of Alzheimer's disease risk
M Seto - 2022 - search.proquest.com
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by
neurodegeneration, memory loss and cognitive impairment. Sporadic late-onset AD is the …
neurodegeneration, memory loss and cognitive impairment. Sporadic late-onset AD is the …