The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

Recent advances have improved our understanding of the renin‐angiotensin system (RAS).
These have included the recognition that angiotensin (A ng)‐(1‐7) is a biologically active …

Abstract Angiotensin (Ang)-(1-7) is a bioactive component of the renin-angiotensin system
that is formed endogenously from either Ang I or Ang II. The first actions described for Ang-(1 …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

The renin-angiotensin system is a major physiological regulator of arterial pressure and
hydro-electrolyte balance. Evidence has now been accumulated that in addition to …

Peptide hormones such as ANG II and endothelin contribute to cardiac remodeling after
myocardial infarction by stimulating myocyte hypertrophy and myofibroblast proliferation. In …

The renin–angiotensin system (RAS) has recently been extended by the addition of a novel
axis consisting of the angiotensin-converting enzyme 2 (ACE2), the heptapeptide …

Recent studies have shown that angiotensin-(1-7)(Ang-[1-7]), which is generated
endogenously from both Ang I and II, is a bioactive component of the renin-angiotensin …

Angiotensin-converting enzyme 2 (ACE2) is a homolog of ACE that preferentially forms
angiotensin-(1–7)[ANG-(1–7)] from angiotensin II (ANG II). Incubation of neonatal rat …

The study of experimental hypertension and the development of drugs with selective
inhibitory effects on the enzymes and receptors constituting the components of the …