Understanding complex systems often requires a bottom-up analysis towards a systems
biology approach. The need to investigate a system, not only as individual components but …

Proteins are composed of evolutionary units called domains; the majority of proteins consist
of at least two domains. These domains and nature of their interactions determine the …

We introduce clustering with overlapping neighborhood expansion (ClusterONE), a method
for detecting potentially overlapping protein complexes from protein-protein interaction data …

The woodland strawberry, Fragaria vesca (2 n= 2 x= 14), is a versatile experimental plant
system. This diminutive herbaceous perennial has a small genome (240 Mb), is amenable to …

Sorghum, an African grass related to sugar cane and maize, is grown for food, feed, fibre
and fuel. We present an initial analysis of the∼ 730-megabase Sorghum bicolor (L.) …

Access to unified datasets of protein and genetic interactions is critical for interrogation of
gene/protein function and analysis of global network properties. BioGRID is a freely …

Observations consisting of measurements on relationships for pairs of objects arise in many
settings, such as protein interaction and gene regulatory networks, collections of author …

A full description of a protein's function requires knowledge of all partner proteins with which
it specifically associates. From a functional perspective,'association'can mean direct physical …

Identification of protein–protein interactions often provides insight into protein function, and
many cellular processes are performed by stable protein complexes. We used tandem …

Protein-protein interaction maps provide a valuable framework for a better understanding of
the functional organization of the proteome. To detect interacting pairs of human proteins …