[HTML][HTML] Long non-coding RNAs in gastric cancer: New emerging biological functions and therapeutic implications

H Tan, S Zhang, J Zhang, L Zhu, Y Chen, H Yang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Gastric cancer (GC) is currently the fourth most common malignancy and the third leading
cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) …

Long non-coding RNAs: Biogenesis, functions, and clinical significance in gastric cancer

Y Liu, W Ding, W Yu, Y Zhang, X Ao, J Wang - Molecular Therapy …, 2021 - cell.com
Gastric cancer (GC) is one of the most prevalent malignant tumor types and the third leading
cause of cancer-related death worldwide. Its morbidity and mortality are very high due to a …

Long non-coding RNA MIR4435-2HG promotes colorectal cancer proliferation and metastasis through miR-206/YAP1 axis

X Dong, Z Yang, H Yang, D Li, X Qiu - Frontiers in oncology, 2020 - frontiersin.org
Objective: Long non-coding RNAs (lncRNAs) are critical to colorectal cancer (CRC)
progression. In the current study, the objective was the exploration of the role played by …

LINC00665 activating Wnt3a/β-catenin signaling by bond with YBX1 promotes gastric cancer proliferation and metastasis

J Wang, D Shen, S Li, Q Li, Q Zuo, J Lu, D Tang… - Cancer Gene …, 2023 - nature.com
Long noncoding RNAs (lncRNAs) play a key role in human cancer development;
nevertheless, the effect of lncRNA LINC00665 on the progression of gastric cancer (GC) still …

Autophagy and gastrointestinal cancers: the behind the scenes role of long non-coding RNAs in initiation, progression, and treatment resistance

R Shafabakhsh, F Arianfar, M Vosough… - Cancer Gene …, 2021 - nature.com
Gastrointestinal (GI) cancers comprise a heterogeneous group of complex disorders that
affect different organs, including esophagus, stomach, gallbladder, liver, biliary tract …

Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils

H Yu, C Chen, F Han, J Tang, M Deng, Y Niu… - Cancer Immunology …, 2022 - AACR
Abstract MIR4435-2HG, also known as LINC00978, has previously been described as an
oncogenic long noncoding RNA (lncRNA). However, we show here that Mir4435-2hg …

Paeonol inhibits the malignancy of Apatinib-resistant gastric cancer cells via LINC00665/miR-665/MAPK1 axis

M Li, O Cai, Y Yu, S Tan - Phytomedicine, 2022 - Elsevier
Background Paeonol is the extractive of Paeonia suffruticosa Andr and is reported to reverse
the chemotherapy resistance of cancer cells. The present study explores the role of paeonol …

Glycolysis-associated lncRNAs identify a subgroup of cancer patients with poor prognoses and a high-infiltration immune microenvironment

KH Ho, TW Huang, CM Shih, YT Lee, AJ Liu, PH Chen… - BMC medicine, 2021 - Springer
Abstract Background Long noncoding (lnc) RNAs and glycolysis are both recognized as key
regulators of cancers. Some lncRNAs are also reportedly involved in regulating glycolysis …

MIR4435-2HG is a potential pan-cancer biomarker for diagnosis and prognosis

C Zhong, Z Xie, L Zeng, C Yuan, S Duan - Frontiers in Immunology, 2022 - frontiersin.org
The lncRNA MIR4435-2 host gene (MIR4435-2HG) is located on human chromosome 2q13,
and its expression is up-regulated in 18 tumors. MIR4435-2HG participates in 6 signaling …

MIR4435-2HG in exosomes promotes gastric carcinogenesis by inducing M2 polarization in macrophages

C Li, Z Chen, J Gao, T Tang, L Zhou, G Zhang… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer (GC) is a cancer with a high mortality rate. lncRNAs play a role in regulating
GC tumorigenesis. In this paper, we analyzed differentially expressed lncRNAs between GC …