Astrocyte development and heterogeneity

OA Bayraktar, LC Fuentealba… - Cold Spring …, 2015 - cshperspectives.cshlp.org
Astrocytes have many roles within the brain parenchyma, and a subpopulation restricted to
germinal niches functions as neural stem cells (NSCs) that produce various types of …

Individual human cortical progenitors can produce excitatory and inhibitory neurons

RN Delgado, DE Allen, MG Keefe, WR Mancia Leon… - Nature, 2022 - nature.com
The cerebral cortex is a cellularly complex structure comprising a rich diversity of neuronal
and glial cell types. Cortical neurons can be broadly categorized into two classes …

Embryonic origin of postnatal neural stem cells

LC Fuentealba, SB Rompani, JI Parraguez, K Obernier… - Cell, 2015 - cell.com
Adult neural stem/progenitor (B1) cells within the walls of the lateral ventricles generate
different types of neurons for the olfactory bulb (OB). The location of B1 cells determines the …

Subcortical origins of human and monkey neocortical interneurons

T Ma, C Wang, L Wang, X Zhou, M Tian, Q Zhang… - Nature …, 2013 - nature.com
Cortical GABAergic inhibitory interneurons have crucial roles in the development and
function of the cerebral cortex. In rodents, nearly all neocortical interneurons are generated …

Conserved rules in embryonic development of cortical interneurons

C Laclef, C Métin - Seminars in cell & developmental biology, 2018 - Elsevier
This review will focus on early aspects of cortical interneurons (cIN) development from
specification to migration and final positioning in the human cerebral cortex. These …

Cortical neural stem cell lineage progression is regulated by extrinsic signaling molecule sonic hedgehog

Y Zhang, G Liu, T Guo, XG Liang, H Du, L Yang… - Cell reports, 2020 - cell.com
Neural stem cells (NSCs) in the prenatal neocortex progressively generate different
subtypes of glutamatergic projection neurons. Following that, NSCs have a major switch in …

Oxidative stress regulates progenitor behavior and cortical neurogenesis

A Chui, Q Zhang, Q Dai, SH Shi - Development, 2020 - journals.biologists.com
Orderly division of radial glial progenitors (RGPs) in the developing mammalian cerebral
cortex generates deep and superficial layer neurons progressively. However, the …

Mechanisms regulating GABAergic neuron development

K Achim, M Salminen, J Partanen - Cellular and molecular life sciences, 2014 - Springer
Neurons using gamma-aminobutyric acid (GABA) as their neurotransmitter are the main
inhibitory neurons in the mature central nervous system (CNS) and show great variation in …

Extracortical origin of some murine subplate cell populations

M Pedraza, A Hoerder-Suabedissen… - Proceedings of the …, 2014 - National Acad Sciences
The subplate layer, the deepest cortical layer in mammals, has important roles in cerebral
cortical development. The subplate contains heterogeneous cell populations that are …

[HTML][HTML] Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex

SN Kim, VV Viswanadham, RN Doan, Y Dou… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The mammalian cerebral cortex shows functional specialization into regions with distinct
neuronal compositions, most strikingly in the human brain, but little is known in about how …