Targeting tumor innervation: premises, promises, and challenges

X Li, X Peng, S Yang, S Wei, Q Fan, J Liu, L Yang… - Cell death …, 2022 - nature.com
A high intratumoral nerve density is correlated with poor survival, high metastasis, and high
recurrence across multiple solid tumor types. Recent research has revealed that cancer cells …

Erythropoietin as candidate for supportive treatment of severe COVID-19

H Ehrenreich, K Weissenborn, M Begemann… - Molecular …, 2020 - Springer
In light of the present therapeutic situation in COVID-19, any measure to improve course and
outcome of seriously affected individuals is of utmost importance. We recap here evidence …

A DNA Nanostructure-Based Neuroprotectant against Neuronal Apoptosis via Inhibiting Toll-like Receptor 2 Signaling Pathway in Acute Ischemic Stroke

M Zhou, T Zhang, B Zhang, X Zhang, S Gao, T Zhang… - ACS …, 2021 - ACS Publications
Ischemic stroke is a main cause of cognitive neurological deficits and disability worldwide
due to a plethora of neuronal apoptosis. Unfortunately, numerous neuroprotectants for …

Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction

G Cai, G Cai, H Zhou, Z Zhuang, K Liu, S Pei… - Stem Cell Research & …, 2021 - Springer
Background Cerebral infarction ranks as the second leading cause of disability and death
globally, and inflammatory response of glial cells is the main cause of brain damage during …

Erythropoietin re-wires cognition-associated transcriptional networks

M Singh, Y Zhao, VD Gastaldi, SM Wojcik… - Nature …, 2023 - nature.com
Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely
hematopoiesis-independent, but underlying mechanisms and physiological role of brain …

Interface‐Stabilized Fiber Sensor for Real‐Time Monitoring of Amniotic Fluid During Pregnancy

Q Li, D Li, J Lu, K Zou, L Wang, Y Jiao… - Advanced …, 2024 - Wiley Online Library
Diseases in pregnancy endanger millions of fetuses worldwide every year. The onset of
these diseases can be early warned by the dynamic abnormalities of biochemicals in …

Erythropoietin and derivatives: Potential beneficial effects on the brain

DC Vittori, ME Chamorro, YV Hernández… - Journal of …, 2021 - Wiley Online Library
Erythropoietin (Epo), the main erythropoiesis‐stimulating factor widely prescribed to
overcome anemia, is also known nowadays for its cytoprotective action on non …

From cradle to grave: neurogenesis, neuroregeneration and neurodegeneration in Alzheimer's and Parkinson's diseases

D Wakhloo, J Oberhauser, A Madira… - Neural regeneration …, 2022 - journals.lww.com
Two of the most common neurodegenerative disorders–Alzheimer's and Parkinson's
diseases–are characterized by synaptic dysfunction and degeneration that culminate in …

Hippocampal neurons respond to brain activity with functional hypoxia

UJ Butt, AA Steixner-Kumar, C Depp, T Sun… - Molecular …, 2021 - nature.com
Physical activity and cognitive challenge are established non-invasive methods to induce
comprehensive brain activation and thereby improve global brain function including mood …

The role of the mTOR pathway in diabetic retinopathy

F Casciano, E Zauli, E Rimondi, M Mura… - Frontiers in …, 2022 - frontiersin.org
The retina, the part of the eye, translates the light signal into an electric current that can be
sent to the brain as visual information. To achieve this, the retina requires fine-tuned …