Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Long non-coding RNAs (lncRNAs) signaling in cancer chemoresistance: from prediction to druggability

GC Eptaminitaki, D Stellas, B Bonavida… - Drug Resistance Updates, 2022 - Elsevier
The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

C Zhong, WJ Jiang, Y Yao, Z Li, Y Li, S Wang… - Nature …, 2024 - nature.com
Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for
many types of cancer. Here we systematically identify genetic drivers underlying …

Recent advances in ovarian cancer: therapeutic strategies, potential biomarkers, and technological improvements

S Akter, MA Rahman, MN Hasan, H Akhter, P Noor… - Cells, 2022 - mdpi.com
Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …

The interactions of docetaxel with tumor microenvironment

R Gupta, MM Kadhim, AT Jalil, MQ Alasheqi… - International …, 2023 - Elsevier
There are several interactions within the tumor microenvironment (TME) that affect the
response of cancer cells to therapy. There are also a large number of cells and secretions in …

Vorinostat (SAHA) and breast cancer: an overview

A Wawruszak, L Borkiewicz, E Okon, W Kukula-Koch… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BC) is the most frequent malignancy diagnosed in 2020
worldwide. Despite significant advances in BC therapy, its pathogenesis is still not fully …

Chitosan-alginate nanoparticles of cabazitaxel: Design, dual-receptor targeting and efficacy in lung cancer model

AK Mehata, MNL Suseela, C Behera, P Kumari… - International Journal of …, 2022 - Elsevier
Cabazitaxel (CZT) loaded chitosan-alginate based (CSA) nanoparticles were developed
with dual targeting functions of both folate receptor and epidermal growth factor receptor …

[HTML][HTML] Autophagy in cancer resistance to paclitaxel: Development of combination strategies

J Škubník, VS Pavlíčková, T Ruml… - Biomedicine & …, 2023 - Elsevier
Paclitaxel, a compound naturally occurring in yew, is a commonly used drug for the
treatment of different types of cancer. Unfortunately, frequent cancer cell resistance …

Natural taxanes: from plant composition to human pharmacology and toxicity

Ľ Nižnanský, D Osinová, R Kuruc… - International journal of …, 2022 - mdpi.com
Biologically active taxanes, present in small-to medium-sized evergreen conifers of various
Taxus species, are widely used for their antioxidant, antimicrobial and anti-inflammatory …

Herbal therapies for cancer treatment: A review of phytotherapeutic efficacy

A Jenča, DK Mills, H Ghasemi, E Saberian… - … : Targets and Therapy, 2024 - Taylor & Francis
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …