Diabetes is associated with vascular injury and the onset of macrovascular complications.
Advanced glycation endproducts (AGEs) and the AGE precursor methylglyoxal (MGO) have …

Osteoarthritis (OA) is a degenerative disease that affects multiple cells and associated
extracellular matrix (ECM). Chondrocytes and chondroextracellular matrix together …

Methylglyoxal (MGO), a reactive α-oxoaldehyde formed in many foods and beverages
during processing and storage, has neurotoxicity. The purpose of this study was to …

Cancer is a disease characterised by uncontrolled growth and proliferation of cells. Tumours
primarily show a higher rate of glucose uptake for lactate production even in the presence of …

Advanced glycation end products (AGEs) are a class of compounds formed by
nonenzymatic interactions between reducing sugars and proteins, lipids, or nucleic acids …

Advanced glycation end products (AGEs) are the final products of the Maillard reaction,
formed through the interaction of carbohydrates and proteins. Reactive dicarbonyl …

The highly reactive compound methylglyoxal (MG) can cause direct damage to cells and
tissues by reacting with cellular macromolecules. MG has been identified as a biomarker …

Osteoarthritis (OA) is a common degenerative disease characterized by the progressive
destruction both articular cartilage and the subchondral bone. The agents that can effectively …

Elevation in blood glucose is common in COVID-19 patients. There is also a high incidence
of new-onset diabetes mellitus (DM) in COVID-19 patients following hospitalization. To date …

Impaired angiogenesis leads to long-term complications and is a major contributor of the
high morbidity in patients with Diabetes Mellitus (DM). Methylglyoxal (MGO) is a glycolysis …