Cell death is a vital process that occurs in billions of cells in the human body every day. This
process helps maintain tissue homeostasis, supports recovery from acute injury, deals with …

Mitogen-activated protein kinases (MAPKs) are key mediators of signaling in fungi,
participating in the response to diverse stresses and in developmental processes. Since the …

RNA-binding proteins (RBPs) bind to and post-transcriptionally regulate the stability of
mRNAs. La-related protein 1 (LARP1) is a conserved RBP that interacts with poly-A-binding …

Data-driven analyses are increasingly valued in modern medicine. We integrate quantitative
proteomics and transcriptomics from over 1,000 post-mortem brains from six cohorts …

Purpose To explore the function of NORAD in bladder cancer (BC), and to verify whether
NORAD could be used as a biomarker to determine preoperative presence of progression …

The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

RNA-binding proteins (RBPs) play critical roles in regulating gene expression by modulating
splicing, RNA stability, and protein translation. Stimulus-induced alterations in RBP function …

Osteoarthritis (OA) is a major degenerative joint disease. Oxidative stress and inflammation
play key roles in the pathogenesis of OA. 3′-Sialyllactose (3′-SL) is derived from human …

Objective To summarise the adverse events (AE) reported in patients with rheumatoid
arthritis (RA) treated with protein kinase inhibitors (PKi), and identify family and molecule …

Albendazole (ABZ) is a microtubule-targeting anthelmintic that acts against a variety of
human cancer cells, but the dependence of its cytotoxicity on non-mitotic effect remains …