Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Roadmap on Label‐Free Super‐Resolution Imaging

VN Astratov, YB Sahel, YC Eldar… - Laser & Photonics …, 2023 - Wiley Online Library
Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …

Super-resolution SRS microscopy with A-PoD

H Jang, Y Li, AA Fung, P Bagheri, K Hoang… - Nature …, 2023 - nature.com
Stimulated Raman scattering (SRS) offers the ability to image metabolic dynamics with high
signal-to-noise ratio. However, its spatial resolution is limited by the numerical aperture of …

Imaging brain tissue architecture across millimeter to nanometer scales

JM Michalska, J Lyudchik, P Velicky… - Nature …, 2024 - nature.com
Mapping the complex and dense arrangement of cells and their connectivity in brain tissue
demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels …

Bringing vibrational imaging to chemical biology with molecular probes

J Du, H Wang, L Wei - 2022 - ACS Publications
As an emerging optical imaging modality, stimulated Raman scattering (SRS) microscopy
provides invaluable opportunities for chemical biology studies using its rich chemical …

Super‐resolution vibrational imaging using expansion stimulated Raman scattering microscopy

L Shi, A Klimas, B Gallagher, Z Cheng, F Fu… - Advanced …, 2022 - Wiley Online Library
Stimulated Raman scattering (SRS) microscopy is an emerging technology that provides
high chemical specificity for endogenous biomolecules and can circumvent common …

Label-free super-resolution imaging techniques

RE Leighton, AM Alperstein… - Annual Review of …, 2022 - annualreviews.org
Biological and material samples contain nanoscale heterogeneities that are unresolvable
with conventional microscopy techniques. Super-resolution fluorescence methods can break …

Far-field super-resolution chemical microscopy

M Tang, Y Han, D Jia, Q Yang, JX Cheng - Light: Science & …, 2023 - nature.com
Far-field chemical microscopy providing molecular electronic or vibrational fingerprint
information opens a new window for the study of three-dimensional biological, material, and …

Single-Molecule Spectroscopy and Super-Resolution Mapping of Physicochemical Parameters in Living Cells

MA Steves, C He, K Xu - Annual Review of Physical Chemistry, 2024 - annualreviews.org
By superlocalizing the positions of millions of single molecules over many camera frames, a
class of super-resolution fluorescence microscopy methods known as single-molecule …

Raman spectroscopy in prostate cancer: techniques, applications and advancements

F Gaba, WJ Tipping, M Salji, K Faulds, D Graham… - Cancers, 2022 - mdpi.com
Simple Summary Raman spectroscopic analysis is a promising and powerful optical
investigative tool to interrogate tissue and/or biofluids for in vitro and in vivo applications …